2-[2-(3-Bromophenyl)ethynyl]thiophene

Base Information

Chemical Name:2-[2-(3-Bromophenyl)ethynyl]thiophene
CAS No.:473580-48-2
Molecular Formula:C₁₂H₇BrS
Molecular Weight:263.158
Hs Code.:
DSSTox Substance ID:DTXSID40465513
Nikkaji Number:J1.821.642F
Wikidata:Q82291517
Mol file:473580-48-2.mol

Synonyms:473580-48-2;2-[2-(3-bromophenyl)ethynyl]thiophene;DTXSID40465513;2-((3-Bromophenyl)ethynyl)thiophene

Suppliers and Price of 2-[2-(3-Bromophenyl)ethynyl]thiophene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-[(3-BROMOPHENYL)ETHYNYL]THIOPHENE 95.00%
5MG
$ 500.74

Total 0 raw suppliers

Chemical Property of 2-[2-(3-Bromophenyl)ethynyl]thiophene

Chemical Property:

PSA：28.24000
LogP:3.91040
XLogP3:4.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:261.94518
Heavy Atom Count:14
Complexity:250

Purity/Quality:: 2-[(3-BROMOPHENYL)ETHYNYL]THIOPHENE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)Br)C#CC2=CC=CS2

Technology Process of 2-[2-(3-Bromophenyl)ethynyl]thiophene

There total 2 articles about 2-[2-(3-Bromophenyl)ethynyl]thiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: diethyl(thiophene)aluminium

: 1-bromo-3-(bromoethynyl)benzene

: 473580-48-2
2-((3-bromophenyl)ethynyl)thiophene

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; 1,2-bis-(diphenylphosphino)ethane; In tetrahydrofuran; at 60 ℃; for 24h; Inert atmosphere;
DOI:10.1016/j.tet.2018.08.050

Reference yield: 62.0%

: 3437-95-4,149762-92-5
2-Iodothiophene

: 591-18-4
1-Bromo-3-iodobenzene

: 1066-54-2
trimethylsilylacetylene

: 473580-48-2
2-((3-bromophenyl)ethynyl)thiophene

Guidance literature:: 2-Iodothiophene; trimethylsilylacetylene; With copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In benzene; at 20 ℃; for 18h;

1-Bromo-3-iodobenzene; With water; 1,8-diazabicyclo[5.4.0]undec-7-ene; In benzene; at 20 ℃; for 18h; Further stages.;
DOI:10.1021/ol026266n