2-(2-Hydroxyphenyl)oxirane

Base Information

• Chemical Name: 2-(2-Hydroxyphenyl)oxirane
• CAS No.: 250597-24-1
• Molecular Formula: C8H8O2
• Molecular Weight: 136.15
• Mol file: 250597-24-1.mol

Synonyms:2-(2-Hydroxyphenyl)oxirane

Chemical Property of 2-(2-Hydroxyphenyl)oxirane

Chemical Property:

• Boiling Point: 185.3±20.0 °C(Predicted)
• PKA: 9.84±0.35(Predicted)
• PSA: 32.76000
• Density: 1.273±0.06 g/cm3(Predicted)
• LogP: 1.46350

Purity/Quality:

97% ^*data from raw suppliers

2-(2-Hydroxyphenyl)oxirane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-(2-Hydroxyphenyl)oxirane is used in the enzymic preparation of self-crosslinking hydroxyphenyl epoxy compounds.

Technology Process of 2-(2-Hydroxyphenyl)oxirane

There total 1 articles about 2-(2-Hydroxyphenyl)oxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(2-bromoacetyl)hydroxybenzene (2491-36-3) → C8H8O2 (250597-24-1) + C8H9BrO2

Guidance literature:

With C₃₇H₃₆AsN₂Ru⁽¹⁺⁾*F₆P^(1-); potassium tert-butylate; In isopropyl alcohol; at 110 ℃; Schlenk technique; Inert atmosphere;

DOI:10.1039/c9nj01220f

Reference yield: 80.0%

C8H8O2 (250597-24-1) → 2-(1-hydroxyethyl)phenol (87804-23-7,62019-23-2)

Guidance literature:

With diphosphorus tetraiodide; tetraethylammonium bromide; water; In dichloromethane; at 20 ℃; for 5h; regioselective reaction;

DOI:10.1080/00397910903219492

Reference yield: 58.0%

nitromethane (75-52-5) + C8H8O2 (250597-24-1) + phenyl isothiocyanate (103-72-0) → 2-[5-(phenylimino)-1,4-oxathian-2-yl]phenol

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 8h;

DOI:10.1055/s-0034-1378277

upstream raw materials:

2-(2-bromoacetyl)hydroxybenzene

Downstream raw materials:

2-(1-hydroxyethyl)phenol