Bicifadine Hydrochloride

Base Information

• Chemical Name: Bicifadine Hydrochloride
• CAS No.: 66504-88-9
• Molecular Formula: C12H16ClN
• Molecular Weight: 209.719
• Mol file: 66504-88-9.mol

Synonyms:Bicifadine Hydrochloride;(1S,5R)-1-(4-Methylphenyl)-

Chemical Property of Bicifadine Hydrochloride

Chemical Property:

• PSA: 12.03000
• LogP: 2.98670
• Storage Temp.: Refrigerator
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

(-)-BicifadineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A novel non-narcotic analgesic drug Bicifadine Hydrochloride is a novel non-narcotic analgesic drug for the treatment of acute pain, chronic pain, and symptoms of neuropathic disorders.

Technology Process of Bicifadine Hydrochloride

There total 1 articles about Bicifadine Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

(-)-bicifadine (83213-67-6) → (1S,5R)-1-(4-methylphenyl)-3-azybicyclo<3.1.0>hexane hydrochloride (66504-88-9)

Guidance literature:

With hydrogenchloride; In ethyl acetate; isopropyl alcohol; at 20 ℃; Product distribution / selectivity;

upstream raw materials:

(-)-bicifadine

Refernces