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α-Etoposide

Base Information Edit
  • Chemical Name:α-Etoposide
  • CAS No.:100007-53-2
  • Molecular Formula:C29H32O13
  • Molecular Weight:588.565
  • Hs Code.:
  • Mol file:100007-53-2.mol
α-Etoposide

Synonyms:Etoposide Impurity C;alpha-Etoposide;(5R,5aR,8aR,9S)-9-[[4,6-O-(1R)-Ethylidene-alpha-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one

Suppliers and Price of α-Etoposide
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • α-Etoposide
  • 10mg
  • $ 1695.00
  • TRC
  • α-Etoposide
  • 1mg
  • $ 215.00
Total 9 raw suppliers
Chemical Property of α-Etoposide Edit
Chemical Property:
  • Boiling Point:798.1±60.0 °C(Predicted) 
  • PKA:9.94±0.40(Predicted) 
  • PSA:160.83000 
  • Density:1.55±0.1 g/cm3(Predicted) 
  • LogP:1.33860 
  • Storage Temp.:-20°C Freezer 
  • Solubility.:Chloroform (Slightly), Methanol (Slightly) 
Purity/Quality:

98% *data from raw suppliers

α-Etoposide *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Uses α-Etoposide, s a cytotoxic agent (anticancer drug), which belongs to the drug type topoisomerase inhibitor. It is also an antineoplastic drug. α-Etoposide, is a cytotoxic agent (anticancer drug), which belongs to the drug type topoisomerase inhibitor. It is also an antineoplastic drug.
Technology Process of α-Etoposide

There total 8 articles about α-Etoposide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With palladium 10% on activated carbon; In 1,4-dioxane; methanol; at 30 ℃; for 4h; Inert atmosphere; Green chemistry;
Guidance literature:
Multi-step reaction with 5 steps
1: pyridine / CH2Cl2 / 2 h / 0 °C
2: MeOH / CH2Cl2 / 20 h / 20 °C
3: Et3N / CH2Cl2 / 2 h / Ambient temperature
4: BF3*Et2O / CH2Cl2 / 1) -20 deg C, 8 h, 2) -10 deg C, 30 min
5: MeOH, zinc acetate dihydrate / 1.5 h / Heating
With pyridine; methanol; boron trifluoride diethyl etherate; zinc diacetate; triethylamine; In dichloromethane;
DOI:10.1021/jo00067a071
Guidance literature:
Multi-step reaction with 2 steps
1: BF3*Et2O / CH2Cl2 / 1) -20 deg C, 8 h, 2) -10 deg C, 30 min
2: MeOH, zinc acetate dihydrate / 1.5 h / Heating
With methanol; boron trifluoride diethyl etherate; zinc diacetate; In dichloromethane;
DOI:10.1021/jo00067a071
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