1-Naphthalenecarboxylicacid,1-amino-1,2,3,4-tetrahydro-,(1S)-(9CI)

Base Information

• Chemical Name: 1-Naphthalenecarboxylicacid,1-amino-1,2,3,4-tetrahydro-,(1S)-(9CI)
• CAS No.: 197379-82-1
• Molecular Formula: C₁₁H₁₃NO₂
• Molecular Weight: 191.23
• Mol file: 197379-82-1.mol

Synonyms:1-Naphthalenecarboxylicacid,1-amino-1,2,3,4-tetrahydro-,(1S)-(9CI)

Chemical Property of 1-Naphthalenecarboxylicacid,1-amino-1,2,3,4-tetrahydro-,(1S)-(9CI)

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 1-Naphthalenecarboxylicacid,1-amino-1,2,3,4-tetrahydro-,(1S)-(9CI)

There total 10 articles about 1-Naphthalenecarboxylicacid,1-amino-1,2,3,4-tetrahydro-,(1S)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

NSC 187220 (57998-96-6) → 1-amino-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (30265-11-3,197379-82-1,197381-49-0,6336-38-5)

Guidance literature:

With barium dihydroxide; In water; at 125 ℃; for 24h;

DOI:10.1002/hlca.19920750522

Reference yield: 83.0%

(S)-1-((S)-1-Phenyl-ethylamino)-1,2,3,4-tetrahydro-naphthalene-1-carboxylic acid amide → (S)-1-amino-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (197379-82-1,197381-49-0,6336-38-5)

Guidance literature:

With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol; for 24h; under 750.06 Torr;

DOI:10.1016/S0040-4020(01)00505-1

Reference yield: 50.0%

rac-1-amino-1-carbamoyl-1,2,3,4-tetrahydronaphthalene → (S)-1-amino-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (197379-82-1,197381-49-0,6336-38-5) + (R)-(+)-1-amino-1-carbamoyl-1,2,3,4-tetrahydronaphthalene

Guidance literature:

With amidase-containing Rhodococcus sp. AJ₂₇₀; nitrile hydratase; In phosphate buffer; at 30 ℃; for 56h; pH=7.0;

DOI:10.1002/adsc.200303219

upstream raw materials:

NSC 187220

3,4-dihydronaphthalene-1(2H)-one

N-[(R)-2'-hydroxy-1'-phenylethyl]-(S)-1-amino-1,2,3,4-tetrahydronaphthalene-1-carboxamide