BenzaMide, 4-[(4-Methyl-1-piperazinyl)Methyl]-N-[6-Methyl-5-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]-3-pyridinyl]-3-(trifluoroMethyl)-

Base Information

Chemical Name:BenzaMide, 4-[(4-Methyl-1-piperazinyl)Methyl]-N-[6-Methyl-5-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]-3-pyridinyl]-3-(trifluoroMethyl)-
CAS No.:895519-90-1
Molecular Formula:C29H29F3N8O
Molecular Weight:562.597
Hs Code.:
Mol file:895519-90-1.mol

Synonyms:BenzaMide, 4-[(4-Methyl-1-piperazinyl)Methyl]-N-[6-Methyl-5-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]-3-pyridinyl]-3-(trifluoroMethyl)-;4-[(4-Methyl-1-piperazinyl)methyl]-N-[6-methyl-5-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-3-pyridinyl]-3-(trifluoromethyl)benzamide

Suppliers and Price of BenzaMide, 4-[(4-Methyl-1-piperazinyl)Methyl]-N-[6-Methyl-5-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]-3-pyridinyl]-3-(trifluoroMethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
Flumatinib >98%
1 g
$ 950.00

DC Chemicals
Flumatinib >98%
250 mg
$ 500.00

DC Chemicals
Flumatinib >98%
100 mg
$ 250.00

Crysdot
Flumatinib 98+%
10mg
$ 62.00

Crysdot
Flumatinib 98+%
5mg
$ 49.00

Crysdot
Flumatinib 98+%
50mg
$ 132.00

ChemScene
Flumatinib 99.94%
10mg
$ 108.00

ChemScene
Flumatinib 99.94%
5mg
$ 84.00

ChemScene
Flumatinib 99.94%
50mg
$ 228.00

American Custom Chemicals Corporation
FLUMATINIB 95.00%
5MG
$ 504.60

Total 12 raw suppliers

Chemical Property of BenzaMide, 4-[(4-Methyl-1-piperazinyl)Methyl]-N-[6-Methyl-5-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]-3-pyridinyl]-3-(trifluoroMethyl)-

Chemical Property:

PSA：102.66000
LogP:5.33690

Purity/Quality:

97% ^*data from raw suppliers

Flumatinib >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of BenzaMide, 4-[(4-Methyl-1-piperazinyl)Methyl]-N-[6-Methyl-5-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]-3-pyridinyl]-3-(trifluoroMethyl)-

There total 6 articles about BenzaMide, 4-[(4-Methyl-1-piperazinyl)Methyl]-N-[6-Methyl-5-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]-3-pyridinyl]-3-(trifluoroMethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 859027-02-4,859282-11-4
4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl) benzoic acid

: 895519-81-0
2-methyl-5-amino-3-(4-pyridin-3-yl)pyrimidin-2-ylamino-pyridine

: 895519-90-1
4-[(4-methylpiperazin-1-yl)methyl]-N-[6-methyl-5-[((4-pyridin-3-yl)pyrimidin-2-yl)amino]pyridin-3-yl]-3-(trifluoromethyl)benzamide

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In water; at 20 ℃;

Reference yield: 94.3%

: 4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzamide

: N-(5-chloro-2-methylpyridin-3-yl)-4-(pyridin-3-yl)pyrimidin-2-amine

: 895519-90-1
4-[(4-methylpiperazin-1-yl)methyl]-N-[6-methyl-5-[((4-pyridin-3-yl)pyrimidin-2-yl)amino]pyridin-3-yl]-3-(trifluoromethyl)benzamide

Guidance literature:: With copper(l) iodide; potassium carbonate; ethylenediamine; tert-butylhydroquinone; In water; N,N-dimethyl-formamide; at 120 ℃; for 6h; Solvent; Reagent/catalyst;

Reference yield:

: 261952-06-1
4-methyl-3-(trifluoromethyl)benzonitrile

: 895519-90-1
4-[(4-methylpiperazin-1-yl)methyl]-N-[6-methyl-5-[((4-pyridin-3-yl)pyrimidin-2-yl)amino]pyridin-3-yl]-3-(trifluoromethyl)benzamide

Guidance literature:: Multi-step reaction with 3 steps

1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrahydrofuran / 6 h / 85 °C

2: palladium diacetate / tetrahydrofuran; acetonitrile / 2 h / 135 °C

3: copper(l) iodide; potassium carbonate; ethylenediamine; tert-butylhydroquinone / water; N,N-dimethyl-formamide / 6 h / 120 °C

With N-Bromosuccinimide; copper(l) iodide; 2,2'-azobis(isobutyronitrile); palladium diacetate; potassium carbonate; ethylenediamine; tert-butylhydroquinone; In tetrahydrofuran; water; N,N-dimethyl-formamide; acetonitrile;