1-Benzyl-5-hydroxy-1,6-dihydropyridin-3(2H)-one

Base Information

Chemical Name:1-Benzyl-5-hydroxy-1,6-dihydropyridin-3(2H)-one
CAS No.:15057-43-9
Molecular Formula:C12H13NO2
Molecular Weight:203.24
Hs Code.:2933399090
DSSTox Substance ID:DTXSID60512558
Nikkaji Number:J254.918B
Mol file:15057-43-9.mol

Synonyms:15057-43-9;1-Benzyl-5-hydroxy-1,6-dihydropyridin-3(2H)-one;1-Benzyl-5-hydroxy-1,2,3,6-tetrahydropyridin-3-one;1-benzyl-5-hydroxy-2,6-dihydropyridin-3-one;1-benzyl-3-oxo-5-hydroxy-1,2,3,6-tetrahydropyridine;SCHEMBL3922841;DTXSID60512558;YZNHGFBTNUJVQD-UHFFFAOYSA-N;MFCD30290472;AKOS037646374;AS-68481;W15269

Suppliers and Price of 1-Benzyl-5-hydroxy-1,6-dihydropyridin-3(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-Benzyl-5-hydroxy-1,6-dihydropyridin-3(2H)-one

Chemical Property:

Boiling Point:346.4±42.0 °C(Predicted)
PKA:5.10±0.40(Predicted)
PSA：40.54000
Density:1.265±0.06 g/cm3(Predicted)
LogP:1.45110
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:203.094628657
Heavy Atom Count:15
Complexity:267

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=CC(=O)CN1CC2=CC=CC=C2)O

Technology Process of 1-Benzyl-5-hydroxy-1,6-dihydropyridin-3(2H)-one

There total 2 articles about 1-Benzyl-5-hydroxy-1,6-dihydropyridin-3(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 15057-40-6
ethyl 2-(benzyl(2-oxopropyl)amino)acetate

: 15057-43-9
1-benzyl-3-oxo-5-hydroxy-1,2,3,6-tetrahydropyridine

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; at 0 - 20 ℃; for 18h;
DOI:10.1021/jo0615091

Reference yield:

: 6436-90-4
ethyl 2-(benzylamino)acetate

: 15057-43-9
1-benzyl-3-oxo-5-hydroxy-1,2,3,6-tetrahydropyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / NaHCO₃ / ethanol / 16 h / 60 °C

2: potassium tert-butoxide / tetrahydrofuran / 18 h / 0 - 20 °C

With potassium tert-butylate; sodium hydrogencarbonate; In tetrahydrofuran; ethanol;
DOI:10.1021/jo0615091