Chemical Property of Mal-PEG2-NHS ester
Chemical Property:
- Boiling Point:524.3±60.0 °C(Predicted)
- PKA:-2.34±0.20(Predicted)
- PSA：119.52000
- Density:1.42±0.1 g/cm3(Predicted)
- LogP:-1.18230
- Solubility.:Soluble in DCM
- Purity/Quality:
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97% *data from raw suppliers
MAL-PEG2-NHSEster *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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Useful:
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Description
Mal-PEG2-NHS ester is a PEG linker containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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Uses
Mal-?PEG2-?NHS Ester is a reagent used in the preparation of antibody-drug conjugates that bind to human-antigen targets in the effort to combat cancers.
