(S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol

Base Information

Chemical Name:(S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol
CAS No.:68643-08-3
Molecular Formula:C₁₆H₂₅NO
Molecular Weight:247.381
Hs Code.:
ChEMBL ID:CHEMBL269004
DSSTox Substance ID:DTXSID801336109
Nikkaji Number:J449.683C
Wikidata:Q4639640
Wikipedia:5-OH-DPAT
Mol file:68643-08-3.mol

Synonyms:CHEMBL269004;SCHEMBL5705486;DTXSID801336109;68643-08-3;BDBM50115277;Q4639640;(S)-(-)-5-hydroxy-2-(N,N-di-n-propylamino)tetralin;(2S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol;(S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol;(2R,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol;(2R,3S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol;(2S,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol;(6S)-6-(Dipropylamino)-5,6,7,8-tetrahydro-1-naphthalenol;(S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol.HCl

Suppliers and Price of (S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol

Chemical Property:

PSA：23.47000
LogP:3.37150
XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:247.193614421
Heavy Atom Count:18
Complexity:237

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCN(CCC)C1CCC2=C(C1)C=CC=C2O
Isomeric SMILES:CCCN(CCC)[C@H]1CCC2=C(C1)C=CC=C2O

Technology Process of (S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol

There total 5 articles about (S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 123-38-6
propionaldehyde

: 58349-15-8,58349-17-0
(S)-5-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride

: 68643-08-3
(2S)-5-hydroxy-2-(di-n-propylamino)tetralin

Guidance literature:: (S)-5-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride; With hydrogen bromide; In water; at 130 ℃; for 3h;

propionaldehyde; With sodium cyanoborohydride; In methanol; at 20 ℃; for 20h;
DOI:10.1016/j.bmc.2019.115262

Reference yield:

: 136655-20-4
(S)-5-OMe-DPAT

: 68643-08-3
(2S)-5-hydroxy-2-(di-n-propylamino)tetralin

Guidance literature:: With boron tribromide; In dichloromethane; Ambient temperature;
DOI:10.1021/jm00380a012

Reference yield:

: 105086-92-8,105086-80-4
(S)-5-methoxy-2-amino-1,2,3,4-tetrahydronaphthalene

: 68643-08-3
(2S)-5-hydroxy-2-(di-n-propylamino)tetralin

Guidance literature:: Multi-step reaction with 2 steps

1: NaBH₃CN / methanol

2: BBr₃ / CH₂Cl₂

With boron tribromide; sodium cyanoborohydride; In methanol; dichloromethane;
DOI:10.1021/jm0498102