4-Bromo-2,6-dimethylquinoline

Base Information

Chemical Name:4-Bromo-2,6-dimethylquinoline
CAS No.:123637-45-6
Molecular Formula:C₁₁H₁₀BrN
Molecular Weight:236.111
Hs Code.:
DSSTox Substance ID:DTXSID40566635
Wikidata:Q82452335
Mol file:123637-45-6.mol

Synonyms:4-Bromo-2,6-dimethylquinoline;123637-45-6;Quinoline, 4-bromo-2,6-dimethyl-;SCHEMBL6766825;DTXSID40566635;VNQOVTVVZJAQBW-UHFFFAOYSA-N;MFCD11505127;SB71400

Suppliers and Price of 4-Bromo-2,6-dimethylquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-BROMO-2,6-DIMETHYLQUINOLINE 95.00%
5MG
$ 504.36

Total 2 raw suppliers

Chemical Property of 4-Bromo-2,6-dimethylquinoline

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
Boiling Point:318.634°C at 760 mmHg
Flash Point:146.505°C
PSA：12.89000
Density:1.427g/cm³
LogP:3.61410
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:234.99966
Heavy Atom Count:13
Complexity:183

Purity/Quality:

97% ^*data from raw suppliers

4-BROMO-2,6-DIMETHYLQUINOLINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(C=C(N=C2C=C1)C)Br

Technology Process of 4-Bromo-2,6-dimethylquinoline

There total 1 articles about 4-Bromo-2,6-dimethylquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 25428-07-3
4-hydroxy-2,6-dimethylquinoline

: 123637-45-6
4-bromo-2,6-dimethylquinoline

Guidance literature:: With N,N-dimethyl-aniline; phosphorus(V) oxybromide; In toluene; at 90 ℃; for 3.5h;
DOI:10.1021/jm00093a007

Reference yield:

: 123637-45-6
4-bromo-2,6-dimethylquinoline

: (S)-2-{4-[(4-Bromo-2-methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-2-fluoro-benzoylamino}-pentanedioic acid diethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: NBS, benzoyl peroxide / CCl₄ / 3 h / 77 °C / Irradiation

2: 2,6-lutidine / dimethylformamide / 18 h / 70 °C

With 2,6-dimethylpyridine; N-Bromosuccinimide; Perbenzoic acid; In tetrachloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm00093a007

Reference yield:

: 123637-45-6
4-bromo-2,6-dimethylquinoline

: 123636-98-6
(S)-2-{4-[(4-Bromo-2-methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid

Guidance literature:: Multi-step reaction with 3 steps

1: NBS, benzoyl peroxide / CCl₄ / 3 h / 77 °C / Irradiation

2: 2,6-lutidine / dimethylformamide / 18 h / 70 °C

3: 65 percent / 1 N aq. NaOH / ethanol / 2.5 h / Ambient temperature

With 2,6-dimethylpyridine; sodium hydroxide; N-Bromosuccinimide; Perbenzoic acid; In tetrachloromethane; ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00093a007