Indazole-1,5-dicarboxylic acid 1-tert-butyl ester 5-Methyl ester

Base Information

Chemical Name:Indazole-1,5-dicarboxylic acid 1-tert-butyl ester 5-Methyl ester
CAS No.:1290181-22-4
Molecular Formula:C14H16N2O4
Molecular Weight:276.28784
Hs Code.:

Synonyms:Indazole-1,5-dicarboxylic acid 1-tert-butyl ester 5-Methyl ester;1-tert-butyl-5-methyl-1H-indazole-1,5-dicarboxylate

Suppliers and Price of Indazole-1,5-dicarboxylic acid 1-tert-butyl ester 5-Methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 6 raw suppliers

Chemical Property of Indazole-1,5-dicarboxylic acid 1-tert-butyl ester 5-Methyl ester

Chemical Property:

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Indazole-1,5-dicarboxylic acid 1-tert-butyl ester 5-Methyl ester

There total 2 articles about Indazole-1,5-dicarboxylic acid 1-tert-butyl ester 5-Methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.9%

: 473416-12-5
methyl 1H-indazole-5-carboxylate

: 34619-03-9
tert-butyldicarbonate

: 1290181-22-4
1-tert-butyl 5-methyl 1H-indazole-1,5-dicarboxylate

Guidance literature:: With triethylamine; In tetrahydrofuran; at 20 ℃; for 2h;

Reference yield: 57.0%

: 473416-12-5
methyl 1H-indazole-5-carboxylate

: 24424-99-5
di-tert-butyl dicarbonate

: 1290181-22-4
1-tert-butyl 5-methyl 1H-indazole-1,5-dicarboxylate

Guidance literature:: With dmap; triethylamine; In tetrahydrofuran; at 20 ℃; for 3h; Cooling;

Reference yield:

: 1290181-22-4
1-tert-butyl 5-methyl 1H-indazole-1,5-dicarboxylate

: tert-butyl 5-(3-(2-(1-trityl-1H-imidazol-4-yl)phenyl)acryloyl)-1H-indazole-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -72 °C / Inert atmosphere

1.2: 2 h / -72 °C / Inert atmosphere

2.1: caesium carbonate / isopropyl alcohol / 20 °C

With n-butyllithium; caesium carbonate; In tetrahydrofuran; hexane; isopropyl alcohol;