Chemical Property of 4-(3-(trifluoromethyl)benzyl)-2H-benzo[b][1,4]thiazin-3(4H)-one
Chemical Property:
- Boiling Point:476.9±45.0 °C(Predicted)
- PKA:0.53±0.20(Predicted)
- PSA：45.61000
- Density:1.375±0.06 g/cm3(Predicted)
- LogP:4.40930
- Storage Temp.:2-8°C
- Solubility.:DMSO: soluble20mg/mL, clear
- XLogP3:4
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:5
- Rotatable Bond Count:2
- Exact Mass:323.05916967
- Heavy Atom Count:22
- Complexity:415
- Purity/Quality:
-
99%, *data from raw suppliers
NS 6180 *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:Xi,N
- Statements:
43-51/53
- Safety Statements:
61
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C1C(=O)N(C2=CC=CC=C2S1)CC3=CC(=CC=C3)C(F)(F)F
-
Uses
NS 6180 increases the proliferation of both A-NK and NA-NK cells. NS 6180 is a new KCa3.1 channel inhibitor that prevents T-cell activation and inflammation in a rat model of inflammatory bowel disease.
