10-Hydroxy-8-pentyl-3-phenyl-1,2,3,4-tetrahydro-5H-phosphinino[3,4-c]chromen-5-one 3-oxide

Base Information

Chemical Name:10-Hydroxy-8-pentyl-3-phenyl-1,2,3,4-tetrahydro-5H-phosphinino[3,4-c]chromen-5-one 3-oxide
CAS No.:77217-78-8
Molecular Formula:C23H25O4P
Molecular Weight:396.416
Hs Code.:
NSC Number:327720
UNII:7VA0383KOY

Synonyms:77217-78-8;7VA0383KOY;NSC327720;NSC 327720;UNII-7VA0383KOY;10-Hydroxy-8-pentyl-3-phenyl-1,2,3,4-tetrahydro-5H-phosphinino[3,4-c]chromen-5-one 3-oxide;NSC-327720;10-Hydroxy-8-pentyl-3-phenyl-1,2,3,4-tetrahydro-5H-phosphinino(3,4-c)chromen-5-one 3-oxide;1,2,3,4-Tetrahydro-10-hydroxy-8-pentyl-3-phenyl-5H-phosphorino(3,4-C)(1)benzopyran-5-one 3-oxide;10-hydroxy-3-oxo-8-pentyl-3-phenyl-2,4-dihydro-1H-phosphinino[3,4-c]chromen-5-one;5H-PHOSPHORINO(3,4-C)(1)BENZOPYRAN-5-ONE, 1,2,3,4-TETRAHYDRO-10-HYDROXY-8-PENTYL-3-PHENYL-, 3-OXIDE

Suppliers and Price of 10-Hydroxy-8-pentyl-3-phenyl-1,2,3,4-tetrahydro-5H-phosphinino[3,4-c]chromen-5-one 3-oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 10-Hydroxy-8-pentyl-3-phenyl-1,2,3,4-tetrahydro-5H-phosphinino[3,4-c]chromen-5-one 3-oxide

Chemical Property:

Vapor Pressure:5.33E-18mmHg at 25°C
Boiling Point:659.5°Cat760mmHg
Flash Point:352.7°C
Density:1.27g/cm³
XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:396.14904627
Heavy Atom Count:28
Complexity:664

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCCCC1=CC(=C2C3=C(CP(=O)(CC3)C4=CC=CC=C4)C(=O)OC2=C1)O

Technology Process of 10-Hydroxy-8-pentyl-3-phenyl-1,2,3,4-tetrahydro-5H-phosphinino[3,4-c]chromen-5-one 3-oxide

There total 3 articles about 10-Hydroxy-8-pentyl-3-phenyl-1,2,3,4-tetrahydro-5H-phosphinino[3,4-c]chromen-5-one 3-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6775-11-7
bis(2-(carbomethoxy)ethyl)phenylphosphine

: 77217-78-8
1,2,3,4-tetrahydro-10-hydroxy-8-n-pentyl-3-phenyl-5H-phosphorino<3,4-c><1>benzopyran-5-one 3-oxide

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) sodium methoxide, 2.) sodium / 1.) toluene, reflux, 2 h, 2.) reflux, 15 h

2: 53 percent / 30percent H₂O₂ / acetone / 0.17 h / 0 °C

3: 1.) conc. H₂SO₄, 2.) Cl₃P=O / 1.) 10 min, 2.) room temperature, 40 h

With sulfuric acid; dihydrogen peroxide; sodium methylate; sodium; trichlorophosphate; In acetone;
DOI:10.1021/ja00398a025

Reference yield:

: 63316-04-1
methyl 4-oxo-1-phenyl-3-phosphorinanecarboxylate

: 77217-78-8
1,2,3,4-tetrahydro-10-hydroxy-8-n-pentyl-3-phenyl-5H-phosphorino<3,4-c><1>benzopyran-5-one 3-oxide

Guidance literature:: Multi-step reaction with 2 steps

1: 53 percent / 30percent H₂O₂ / acetone / 0.17 h / 0 °C

2: 1.) conc. H₂SO₄, 2.) Cl₃P=O / 1.) 10 min, 2.) room temperature, 40 h

With sulfuric acid; dihydrogen peroxide; trichlorophosphate; In acetone;
DOI:10.1021/ja00398a025

Reference yield:

: 500-66-3
Olivetol

: 67976-13-0
methyl 4-oxo-1-phenyl-3-phosphorinanecarboxylate 1-oxide

: 77217-78-8
1,2,3,4-tetrahydro-10-hydroxy-8-n-pentyl-3-phenyl-5H-phosphorino<3,4-c><1>benzopyran-5-one 3-oxide

Guidance literature:: With sulfuric acid; trichlorophosphate; Yield given. Multistep reaction; 1.) 10 min, 2.) room temperature, 40 h;
DOI:10.1021/ja00398a025