4-(1-(Diphenylmethyl)-1-methoxybutyl)-1H-imidazole

Base Information

Chemical Name:4-(1-(Diphenylmethyl)-1-methoxybutyl)-1H-imidazole
CAS No.:106147-71-1
Molecular Formula:C₂₁H₂₄N₂O
Molecular Weight:320.434
Hs Code.:
DSSTox Substance ID:DTXSID10909939
Mol file:106147-71-1.mol

Synonyms:106147-71-1;5-(2-methoxy-1,1-diphenylpentan-2-yl)-1H-imidazole;4-(1-(Diphenylmethyl)-1-methoxybutyl)-1H-imidazole;BRN 4197914;5-[1-(DIPHENYLMETHYL)-1-METHOXYBUTYL]-1H-IMIDAZOLE;4(5)-(2-(1,1-Diphenyl-2-methoxy)pentyl)imidazole;1H-Imidazole, 4-(1-(diphenylmethyl)-1-methoxybutyl)-;4-[1-(Diphenylmethyl)-1-methoxybutyl]-1H-imidazole;DTXSID10909939;LS-78541;FT-0667662

Suppliers and Price of 4-(1-(Diphenylmethyl)-1-methoxybutyl)-1H-imidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-[1-(Diphenylmethyl)-1-methoxybutyl]-1H-imidazole
25mg
$ 1230.00

Biosynth Carbosynth
4-[1-(Diphenylmethyl)-1-methoxybutyl]-1H-imidazole
25 mg
$ 1529.00

Biosynth Carbosynth
4-[1-(Diphenylmethyl)-1-methoxybutyl]-1H-imidazole
10 mg
$ 840.90

Biosynth Carbosynth
4-[1-(Diphenylmethyl)-1-methoxybutyl]-1H-imidazole
5 mg
$ 462.50

Biosynth Carbosynth
4-[1-(Diphenylmethyl)-1-methoxybutyl]-1H-imidazole
2 mg
$ 254.40

Biosynth Carbosynth
4-[1-(Diphenylmethyl)-1-methoxybutyl]-1H-imidazole
1 mg
$ 139.90

Total 3 raw suppliers

Chemical Property of 4-(1-(Diphenylmethyl)-1-methoxybutyl)-1H-imidazole

Chemical Property:

Vapor Pressure:9.27E-08mmHg at 25°C
Boiling Point:446.9°Cat760mmHg
Flash Point:160.5°C
PSA：37.91000
Density:1.098g/cm³
LogP:4.88360
XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:7
Exact Mass:320.188863393
Heavy Atom Count:24
Complexity:345

Purity/Quality:

97% ^*data from raw suppliers

5-[1-(Diphenylmethyl)-1-methoxybutyl]-1H-imidazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCC(C1=CN=CN1)(C(C2=CC=CC=C2)C3=CC=CC=C3)OC
Uses 5-[1-(Diphenylmethyl)-1-methoxybutyl]-1H-imidazole is used for the synthesis Used for the synthesis of 4(5)-(2,2-diphenylethyl)imidazole as new α2-adrenoreceptor antagonist and norepinephrine uptake inhibitor.

Technology Process of 4-(1-(Diphenylmethyl)-1-methoxybutyl)-1H-imidazole

There total 5 articles about 4-(1-(Diphenylmethyl)-1-methoxybutyl)-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

: 132287-54-8
4-<2-(1,1-diphenyl-2-methoxy)-pentyl>-1-tritylimidazole

: 106147-71-1
4(5)-<2-(1,1-diphenyl-2-methoxy)-pentyl>imidazole

Guidance literature:: With acetic acid; Heating;
DOI:10.1016/0223-5234(90)90180-B

Reference yield:

: 4-(1-hydroxy-butyl)-1-tritylimidazole

: 106147-71-1
4(5)-<2-(1,1-diphenyl-2-methoxy)-pentyl>imidazole

Guidance literature:: Multi-step reaction with 4 steps

1: 93 percent / MnO₂ / dioxane / 1 h / Heating

2: 1.) BuLi / 1.) hexane, THF, 0 deg C, 2.) RT, 2 h

3: 1.) BuLi / 1.) THF, hexane, 2.) RT, 0.5 h

4: 23 percent / 66percent aq. acetic acid / Heating

With manganese(IV) oxide; n-butyllithium; acetic acid; In 1,4-dioxane;
DOI:10.1016/0223-5234(90)90180-B

Reference yield:

: 101-81-5
Diphenylmethane

: 106147-71-1
4(5)-<2-(1,1-diphenyl-2-methoxy)-pentyl>imidazole

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) BuLi / 1.) hexane, THF, 0 deg C, 2.) RT, 2 h

2: 1.) BuLi / 1.) THF, hexane, 2.) RT, 0.5 h

3: 23 percent / 66percent aq. acetic acid / Heating

With n-butyllithium; acetic acid;
DOI:10.1016/0223-5234(90)90180-B