(R)-2-Ethyl-piperazine

Base Information

Chemical Name:(R)-2-Ethyl-piperazine
CAS No.:393781-72-1
Molecular Formula:C6H14N2
Molecular Weight:114.19
Hs Code.:2933599590
DSSTox Substance ID:DTXSID401314523
Mol file:393781-72-1.mol

Synonyms:(R)-2-ETHYL-PIPERAZINE;(2R)-2-ethylpiperazine;393781-72-1;(R)-2-ethylpiperazine;(3R)-3-ethylpiperazine;(R)-2-ETHYL-PIPERAZINE-2HCl;SCHEMBL336970;DXOHZOPKNFZZAD-ZCFIWIBFSA-N;DTXSID401314523;AKOS006282374;AKOS007930595

Suppliers and Price of (R)-2-Ethyl-piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
(R)-2-Ethylpiperazine 95%
1 g
$ 832.00

SynQuest Laboratories
(R)-2-Ethylpiperazine 95%
250 mg
$ 328.00

Crysdot
(R)-2-Ethylpiperazine 97%
5g
$ 693.00

Apolloscientific
(R)-2-Ethyl-piperazine 95%
1g
$ 520.00

Apolloscientific
(R)-2-Ethyl-piperazine 95%
250mg
$ 205.00

Alichem
(R)-2-Ethylpiperazine
5g
$ 700.00

Total 3 raw suppliers

Chemical Property of (R)-2-Ethyl-piperazine

Chemical Property:

Boiling Point:169.5±8.0 °C(Predicted)
PKA:9.31±0.40(Predicted)
PSA：24.06000
Density:0.839±0.06 g/cm3(Predicted)
LogP:0.61540
XLogP3:0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:114.115698455
Heavy Atom Count:8
Complexity:63.5

Purity/Quality:

97% ^*data from raw suppliers

(R)-2-Ethylpiperazine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC1CNCCN1
Isomeric SMILES:CC[C@@H]1CNCCN1

Technology Process of (R)-2-Ethyl-piperazine

There total 2 articles about (R)-2-Ethyl-piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 61316-67-4
(R)-3-Ethyl-piperazine-2,5-dione

: 393781-72-1
(R)-2-ethylpiperazine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 65 ℃; for 16h;
DOI:10.1021/jm060065y

Reference yield:

: 900183-91-7
[2-(9H-fluoren-9-ylmethoxycarbonylamino)-butyrylamino]-acetic acid methyl ester

: 393781-72-1
(R)-2-ethylpiperazine

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / piperidine / CH₂Cl₂ / 6 h / 20 °C

2: 62 percent / LiAlH₄ / tetrahydrofuran / 16 h / 65 °C

With piperidine; lithium aluminium tetrahydride; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm060065y

Reference yield:

: 393781-72-1
(R)-2-ethylpiperazine

: 1204978-02-8
3-benzyl-6-chloro-4,5-dimethylpyridazine

: 1204978-29-9
(R)-3-benzyl-6-(3-ethylpiperazin-1-yl)-4,5-dimethylpyridazine

Guidance literature:: With triethylamine; In 1,4-dioxane; 1-methyl-pyrrolidin-2-one; at 190 ℃; Microwave irradiation;
DOI:10.1002/cmdc.201300217