1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(4-(diphenylmethyl)-1-piperazinyl)ethyl)-3-(2-methylpropyl)-

Base Information

Chemical Name:1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(4-(diphenylmethyl)-1-piperazinyl)ethyl)-3-(2-methylpropyl)-
CAS No.:110480-48-3
Molecular Formula:C₂₈H₃₄N₆O₂
Molecular Weight:486.617
Hs Code.:
DSSTox Substance ID:DTXSID40149260
Wikidata:Q83014996

Synonyms:BRN 5676668;1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(4-(diphenylmethyl)-1-piperazinyl)ethyl)-3-(2-methylpropyl)-;110480-48-3;1H-Purine-2,6-dione, 8-(2-(4-(diphenylmethyl)-1-piperazinyl)ethyl)-3,7-dihydro-3-(2-methypropyl)-;SCHEMBL10959948;DTXSID40149260;LS-126963

Suppliers and Price of 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(4-(diphenylmethyl)-1-piperazinyl)ethyl)-3-(2-methylpropyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(4-(diphenylmethyl)-1-piperazinyl)ethyl)-3-(2-methylpropyl)-

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.221g/cm³
XLogP3:4.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:486.27432435
Heavy Atom Count:36
Complexity:724

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CN1C2=C(C(=O)NC1=O)NC(=N2)CCN3CCN(CC3)C(C4=CC=CC=C4)C5=CC=CC=C5

Technology Process of 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(4-(diphenylmethyl)-1-piperazinyl)ethyl)-3-(2-methylpropyl)-

There total 7 articles about 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(4-(diphenylmethyl)-1-piperazinyl)ethyl)-3-(2-methylpropyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: 841-77-0
diphenylmethylpiperazine

: 110480-65-4
8-(2-Bromo-ethyl)-3-isobutyl-3,7-dihydro-purine-2,6-dione

: 110480-48-3
3-isobutyl-8-[2-(4-diphenylmethylpiperazinyl)ethyl]xanthine

Guidance literature:: In methanol; for 20h; Heating;
DOI:10.1016/0223-5234(87)90056-0

Reference yield:

: 54052-65-2
1-isobutyl-5-nitroso-6-amino uracil

: 110480-48-3
3-isobutyl-8-[2-(4-diphenylmethylpiperazinyl)ethyl]xanthine

Guidance literature:: Multi-step reaction with 5 steps

1: 88 percent / H₂ / Raney-NiW-2 / methanol / 4 h / 5320 Torr

2: 98 percent / 1.) 100 deg C, 4 h; 2.) 20 deg C, 20 h

3: 55 percent / 12N NaOH / H₂O / 2 h / 100 °C

4: 82 percent / 48percent HBr, HBr (gas) / 20 h / Heating

5: 30 percent / methanol / 20 h / Heating

With sodium hydroxide; hydrogen bromide; hydrogen; Raney-NiW-2; In methanol; water;
DOI:10.1016/0223-5234(87)90056-0

Reference yield:

: 54052-62-9,321890-32-8
5,6-diamino-1-(2-methylpropyl)-2,4-(1H,3H)-pyrimidine dione

: 110480-48-3
3-isobutyl-8-[2-(4-diphenylmethylpiperazinyl)ethyl]xanthine

Guidance literature:: Multi-step reaction with 4 steps

1: 98 percent / 1.) 100 deg C, 4 h; 2.) 20 deg C, 20 h

2: 55 percent / 12N NaOH / H₂O / 2 h / 100 °C

3: 82 percent / 48percent HBr, HBr (gas) / 20 h / Heating

4: 30 percent / methanol / 20 h / Heating

With sodium hydroxide; hydrogen bromide; In methanol; water;
DOI:10.1016/0223-5234(87)90056-0