2,3-Oxiranedicarboxylic acid, 2-Methyl-, diMethyl ester,(2R,3R)-rel-

Base Information

• Chemical Name: 2,3-Oxiranedicarboxylic acid, 2-Methyl-, diMethyl ester,(2R,3R)-rel-
• CAS No.: 53282-74-9
• Molecular Formula: C7H10O5
• Molecular Weight: 174.15
• Mol file: 53282-74-9.mol

Synonyms:2,3-Oxiranedicarboxylic acid, 2-Methyl-, diMethyl ester,(2R,3R)-rel-

Chemical Property of 2,3-Oxiranedicarboxylic acid, 2-Methyl-, diMethyl ester,(2R,3R)-rel-

Chemical Property:

• PSA: 65.13000
• LogP: -0.51010

Purity/Quality:

NLT 98% ^*data from raw suppliers

2,3-Oxiranedicarboxylicacid,2-methyl-,dimethylester,(2R,3R)-rel- ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-Oxiranedicarboxylic acid, 2-Methyl-, diMethyl ester,(2R,3R)-rel-

There total 5 articles about 2,3-Oxiranedicarboxylic acid, 2-Methyl-, diMethyl ester,(2R,3R)-rel- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

dimethyl 2-(tert-butylperoxy)-2-methylsuccinate → dimethyl cis-epoxymethylsuccinate (53282-74-9)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium bromide; In acetonitrile; at 20 ℃; for 1h; Reagent/catalyst; diastereoselective reaction; Catalytic behavior; Inert atmosphere;

DOI:10.1016/j.tetlet.2016.07.034

Reference yield:

dimethyl 2-(tert-butylperoxy)-2-methylsuccinate → dimethyl cis-epoxymethylsuccinate (53282-74-9) + dimethyl trans-epoxymethylsuccinate (53282-74-9)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; [2.2.2]cryptande; lithium bromide; In acetonitrile; at 20 ℃; for 1h; Reagent/catalyst; Catalytic behavior; Mechanism; Inert atmosphere;

DOI:10.1016/j.tetlet.2016.07.034

Reference yield:

dimethyl 2-(tert-butylperoxy)-2-methylsuccinate → dimethyl cis-epoxymethylsuccinate (53282-74-9) + dimethyl trans-epoxymethylsuccinate (53282-74-9)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; [2.2.2]cryptande; lithium bromide; In acetonitrile; at 20 ℃; for 1h; Reagent/catalyst; Catalytic behavior; Mechanism; Inert atmosphere;

DOI:10.1016/j.tetlet.2016.07.034

upstream raw materials:

(2S,3R)-2-Hydroxy-3-methylbernsteinsaeure-dimethylester

Refernces

• 1、 Zong, Zhenzhen,Lu, Shenglin,Wang, Wenxiao,Li, Zhiping. "Iron-catalyzed alkoxycarbonylation–peroxidation of alkenes with carbazates and T-Hydro". supporting information. p. 6719 - 6721. Retrieved 2018/05/14.