Boc-DL-2-aminoheptanedioic acid

Base Information

• Chemical Name: Boc-DL-2-aminoheptanedioic acid
• CAS No.: 1027776-55-1
• Molecular Formula: C₁₂H₂₁NO₆
• Molecular Weight: 275.302
• Hs Code.: 2922499990
• Mol file: 1027776-55-1.mol

Synonyms:Boc-DL-2-aminoheptanedioic acid

Chemical Property of Boc-DL-2-aminoheptanedioic acid

Chemical Property:

• PSA: 116.42000
• LogP: 1.81370

Purity/Quality:

99% ^*data from raw suppliers

Boc-DL-2-aminoheptanedioic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Boc-DL-2-aminoheptanedioic acid

There total 2 articles about Boc-DL-2-aminoheptanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

1-tert-butyl 2-methyl 7-oxoazepane-1,2-dicarboxylate → 2-[[(1,1-dimethylethoxy)carbonyl]amino]heptanedioic acid (1027776-55-1)

Guidance literature:

With dihydrogen peroxide; lithium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 24h;

DOI:10.1021/acs.cgd.9b00116

Reference yield: 71.0%

alpha-aminopimelic acid (627-76-9,3721-85-5) + di-tert-butyl dicarbonate (24424-99-5) → 2-[[(1,1-dimethylethoxy)carbonyl]amino]heptanedioic acid (1027776-55-1)

Guidance literature:

With triethylamine; In water; N,N-dimethyl-formamide; for 1h;

DOI:10.1021/ja209018u

upstream raw materials:

alpha-aminopimelic acid

di-tert-butyl dicarbonate