3-Bromo-5-(2-methoxyethoxy)benzaldehyde

Base Information

Chemical Name:3-Bromo-5-(2-methoxyethoxy)benzaldehyde
CAS No.:1160184-91-7
Molecular Formula:C10H11BrO3
Molecular Weight:259.1
Hs Code.:2913000090
DSSTox Substance ID:DTXSID90700087
Wikidata:Q82631269
Mol file:1160184-91-7.mol

Synonyms:3-BROMO-5-(2-METHOXYETHOXY)BENZALDEHYDE;1160184-91-7;Benzaldehyde, 3-bromo-5-(2-methoxyethoxy)-;SCHEMBL1347260;DTXSID90700087;JLXJZTYRHDRZHK-UHFFFAOYSA-N;FT-0715679

Suppliers and Price of 3-Bromo-5-(2-methoxyethoxy)benzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-Bromo-5-(2-methoxyethoxy)benzaldehyde 95+%
5g
$ 823.00

American Custom Chemicals Corporation
3-BROMO-5-(2-METHOXYETHOXY)BENZALDEHYDE 95.00%
5MG
$ 505.56

Total 6 raw suppliers

Chemical Property of 3-Bromo-5-(2-methoxyethoxy)benzaldehyde

Chemical Property:

PSA：35.53000
LogP:2.28680
Storage Temp.:2-8°C
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:257.98916
Heavy Atom Count:14
Complexity:175

Purity/Quality:

98%min ^*data from raw suppliers

3-Bromo-5-(2-methoxyethoxy)benzaldehyde 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COCCOC1=CC(=CC(=C1)C=O)Br

Technology Process of 3-Bromo-5-(2-methoxyethoxy)benzaldehyde

There total 2 articles about 3-Bromo-5-(2-methoxyethoxy)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 1160184-89-3
1,3-dibromo-5-(2-methoxyethoxy)benzene

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 1160184-91-7
3-bromo-5-(2-methoxyethoxy)benzaldehyde

Guidance literature:: With n-butyllithium; butyl magnesium bromide; In tetrahydrofuran; hexane; toluene; at 3 - 5 ℃; for 0.916667h; Cooling with ice;

1,3-dibromo-5-(2-methoxyethoxy)benzene; In tetrahydrofuran; hexane; toluene; at 0 - 3 ℃;

N,N-dimethyl-formamide; With hydrogenchloride; more than 3 stages;

Reference yield:

: 626-41-5
3,5-dibromophenol

: 1160184-91-7
3-bromo-5-(2-methoxyethoxy)benzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 9 h / 80 °C / Inert atmosphere

2.1: n-butyllithium; butyl magnesium bromide / toluene; tetrahydrofuran; hexane / 3 h / 0 °C / Inert atmosphere

2.2: 2.67 h / 0 °C / Inert atmosphere

With n-butyllithium; butyl magnesium bromide; potassium carbonate; In tetrahydrofuran; hexane; N,N-dimethyl-formamide; toluene;
DOI:10.1016/j.bmc.2018.02.008

Reference yield: 77.0%

: 165059-42-7,934342-48-0
2-(3-methoxy-propenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

: 1160184-91-7
3-bromo-5-(2-methoxyethoxy)benzaldehyde

: 1223461-29-7
C₁₄H₁₈O₄

Guidance literature:: With bis(triphenylphosphine)palladium dibromide; sodium carbonate; In water; N,N-dimethyl-formamide; at 80 ℃; for 3h;
DOI:10.1016/j.bmcl.2010.02.036