Gal-PUGNAc

Base Information

• Chemical Name: Gal-PUGNAc
• CAS No.: 1145878-98-3
• Molecular Formula: C15H19N3O7
• Molecular Weight: 353.332
• Mol file: 1145878-98-3.mol

Synonyms:2-(AcetylaMino)-2-deoxy-N-[[(phenylaMino)carbonyl]oxy]-D-galactoniMidic Acid δ-Lactone;Galacto-PUGNAc;Gal-PUGNAc

Chemical Property of Gal-PUGNAc

Chemical Property:

• PKA: 12.30±0.70(Predicted)
• PSA: 156.69000
• Density: 1.53±0.1 g/cm3(Predicted)
• LogP: 0.02010
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

95% ^*data from raw suppliers

Galacto-PUGNAc ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Galacto-PUGNAc is a highly selective inhibitor for β-hexosaminidases HEXA and HEXB is cell-permeable. Galacto-PUGNAc is able to modulate the activity of HEXA and HEXB in tissue culture, increasing ganglioside GM2 levels in neuroblastoma cells

Technology Process of Gal-PUGNAc

There total 1 articles about Gal-PUGNAc which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

O-(3,4,6-tri-O-acetyl-2-deoxy-2-N-acetyl-D-galactopyranosylidene)amino N-phenylcarbamate (1145879-04-4) → O-(2-deoxy-2-N-acetyl-D-galactopyranosylidene)amino N-phenylcarbamate (1145878-98-3,132063-05-9,872611-16-0)

Guidance literature:

With ammonia; In methanol; at 0 ℃; for 2h;

DOI:10.1002/anie.200804583

upstream raw materials:

O-(3,4,6-tri-O-acetyl-2-deoxy-2-N-acetyl-D-galactopyranosylidene)amino N-phenylcarbamate