SYNTHALIN SULFATE

Base Information

• Chemical Name: SYNTHALIN SULFATE
• CAS No.: 301-15-5
• Molecular Formula: C12H28 N6 . 2 Cl H
• Molecular Weight: 329.316
• Hs Code.: 2925290090
• Mol file: 301-15-5.mol

Synonyms:Guanidine,1,1'-decamethylenedi-, dihydrochloride (7CI,8CI); Guanidine,N,N'''-1,10-decanediylbis-, dihydrochloride (9CI);1,1'-Decamethylenediguanidine dihydrochloride; 1,1'-Decamethylenediguanidiniumdichloride; Anticoman; Decamethylenediguanidine dihydrochloride; Riddobetes;Synthalin; Synthalin A

Chemical Property of SYNTHALIN SULFATE

Chemical Property:

• Boiling Point: 462.2°Cat760mmHg
• Flash Point: 233.3°C
• PSA: 123.80000
• Density: 1.15g/cm³
• LogP: 4.25720
• Storage Temp.: Store at RT

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of SYNTHALIN SULFATE

There total 4 articles about SYNTHALIN SULFATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1,10-bis[(3-amino-1,2,4-oxadiazol-5-one)-4-yl]decane (1598406-60-0) → 1,10-bis(guanidino)decane dihydrochloride (301-15-5)

Guidance literature:

1,10-bis[(3-amino-1,2,4-oxadiazol-5-one)-4-yl]decane; With acetic acid; zinc; In methanol; water; at 60 ℃; for 2h; Inert atmosphere;

With hydrogenchloride; In methanol; water; at 20 ℃; for 0.25h; Inert atmosphere;

DOI:10.1002/cmdc.201300419

Reference yield:

diaminodecane (646-25-3) → 1,10-bis(guanidino)decane dihydrochloride (301-15-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: triethylamine / diethyl ether; ethanol / 0 - 20 °C / Inert atmosphere

2.1: triethylamine / chloroform / 1 h / 0 - 20 °C / Inert atmosphere

3.1: hydroxylamine hydrochloride; triethylamine / N,N-dimethyl-formamide / 0.25 h / 20 °C / Inert atmosphere

4.1: zinc; acetic acid / methanol; water / 2 h / 60 °C / Inert atmosphere

4.2: 0.25 h / 20 °C / Inert atmosphere

With hydroxylamine hydrochloride; acetic acid; triethylamine; zinc; In methanol; diethyl ether; ethanol; chloroform; water; N,N-dimethyl-formamide;

DOI:10.1002/cmdc.201300419

Reference yield:

decyl-1,10-dicyanamide (2188-10-5) → 1,10-bis(guanidino)decane dihydrochloride (301-15-5)

Guidance literature:

Multi-step reaction with 3 steps

1.1: triethylamine / chloroform / 1 h / 0 - 20 °C / Inert atmosphere

2.1: hydroxylamine hydrochloride; triethylamine / N,N-dimethyl-formamide / 0.25 h / 20 °C / Inert atmosphere

3.1: zinc; acetic acid / methanol; water / 2 h / 60 °C / Inert atmosphere

3.2: 0.25 h / 20 °C / Inert atmosphere

With hydroxylamine hydrochloride; acetic acid; triethylamine; zinc; In methanol; chloroform; water; N,N-dimethyl-formamide;

DOI:10.1002/cmdc.201300419

upstream raw materials:

diaminodecane

decyl-1,10-dicyanamide

decyl-1,10-diethylcyanocarbamate

1,10-bis[(3-amino-1,2,4-oxadiazol-5-one)-4-yl]decane

Refernces