(2R,3S)-ethyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,3-dihydroxy-2-methylpropanoate

Base Information

• Chemical Name: (2R,3S)-ethyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,3-dihydroxy-2-methylpropanoate
• CAS No.: 93636-26-1
• Molecular Formula: C11H20O6
• Molecular Weight: 248.276
• Mol file: 93636-26-1.mol

Synonyms:(2R,3S)-ethyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,3-dihydroxy-2-methylpropanoate

Chemical Property of (2R,3S)-ethyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,3-dihydroxy-2-methylpropanoate

Chemical Property:

• Melting Point: 67 - 68 °C (light petroleum)
• PSA: 85.22000
• LogP: -0.18710

Purity/Quality:

NLT 98% ^*data from raw suppliers

(2R,3S)-ethyl3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,3-dihydroxy-2-methylpropanoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,3S)-ethyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,3-dihydroxy-2-methylpropanoate

There total 5 articles about (2R,3S)-ethyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,3-dihydroxy-2-methylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

ethyl cis-2,3-dideoxy-4,5-O-isopropylidene-2-C-methyl-DL-glycero-pent-2-enonate (93714-02-4) → ethyl 4,5-O-isopropylidene-2-C-methyl-DL-lyxonate (93635-76-8,93636-09-0,93636-10-3,93636-11-4,93636-12-5,93636-26-1,1946820-88-7) + ethyl 4,5-O-isopropylidene-2-C-methyl-DL-ribonate (93635-76-8,93636-09-0,93636-10-3,93636-11-4,93636-12-5,93636-26-1,1946820-88-7)

Guidance literature:

With osmium(VIII) oxide; potassium chlorate; acetic acid; In ethanol; water; for 24h; Ambient temperature;

DOI:10.1016/0008-6215(84)85302-1

Reference yield: 33.0%

ethyl cis-2,3-dideoxy-4,5-O-isopropylidene-2-C-methyl-DL-glycero-pent-2-enonate (93714-02-4) → ethyl 4,5-O-isopropylidene-2-C-methyl-DL-lyxonate (93635-76-8,93636-09-0,93636-10-3,93636-11-4,93636-12-5,93636-26-1,1946820-88-7) + ethyl 4,5-O-isopropylidene-2-C-methyl-DL-ribonate (93635-76-8,93636-09-0,93636-10-3,93636-11-4,93636-12-5,93636-26-1,1946820-88-7)

Guidance literature:

With osmium(VIII) oxide; potassium chlorate; acetic acid; In ethanol; water; for 24h; Ambient temperature;

DOI:10.1016/0008-6215(84)85302-1

Reference yield: 22.0%

ethyl trans-2,3-dideoxy-4,5-O-isopropylidene-2-C-methyl-DL-glycero-pent-2-enonate (93714-03-5) → ethyl 4,5-O-isopropylidene-2-C-methyl-DL-arabinonate (93635-76-8,93636-09-0,93636-10-3,93636-11-4,93636-12-5,93636-26-1,1946820-88-7) + ethyl 4,5-O-isopropylidene-2-C-methyl-DL-xylonate (93635-76-8,93636-09-0,93636-10-3,93636-11-4,93636-12-5,93636-26-1,1946820-88-7)

Guidance literature:

With osmium(VIII) oxide; potassium chlorate; acetic acid; In ethanol; water; for 24h; Ambient temperature;

DOI:10.1016/0008-6215(84)85302-1

upstream raw materials:

ethyl trans-2,3-dideoxy-4,5-O-isopropylidene-2-C-methyl-DL-glycero-pent-2-enonate

ethyl cis-2,3-dideoxy-4,5-O-isopropylidene-2-C-methyl-DL-glycero-pent-2-enonate

ethyl trans-2,3-dideoxy-4,5-O-isopropylidene-2-C-methyl-D-glycero-pent-2-enonate

Downstream raw materials:

3,4-O-isopropylidene-2-C-methyl-DL-arabinono-1,5-lactone

ethyl 2,3:4,5-di-O-isopropylidene-2-C-methyl-DL-arabinonate

2-C-methyl-DL-arabinono-1,4-lactone

2-C-methyl-DL-lyxono-1,4-lactone