2α-Methyl-5α-cholestan-3α-ol acetate

Base Information

• Chemical Name: 2α-Methyl-5α-cholestan-3α-ol acetate
• CAS No.: 20997-52-8
• Molecular Weight: 444.73
• Mol file: 20997-52-8.mol

Synonyms:2α-Methyl-5α-cholestan-3α-ol acetate

Chemical Property of 2α-Methyl-5α-cholestan-3α-ol acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2α-Methyl-5α-cholestan-3α-ol acetate

There total 9 articles about 2α-Methyl-5α-cholestan-3α-ol acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Cholest-4-en-3-one (601-57-0) → 3β-acetoxy-2α-methyl-5α-cholestane (20997-52-8,37163-88-5)

Guidance literature:

Multi-step reaction with 3 steps

1: oxalic acid diethyl ester / anschliessend Behandeln mit CH₃I

2: diethyl ether; lithium / in fluessigem NH₃

3: pyridine

With pyridine; diethyl ether; lithium; oxalic acid diethyl ester;

DOI:10.1021/ja01552a051

Reference yield:

dihydrocholesterone (566-88-1) → 3β-acetoxy-2α-methyl-5α-cholestane (20997-52-8,37163-88-5)

Guidance literature:

Multi-step reaction with 3 steps

1: NaH; benzene / anschl. mit CH₃I und K₂CO₃ in Aceton

2: LiAlH₄; diethyl ether

3: pyridine

With pyridine; lithium aluminium tetrahydride; diethyl ether; sodium hydride; benzene;

DOI:10.1021/ja01552a051

Reference yield:

2α-methylcholest-4-en-3-one (54446-38-7) → 3β-acetoxy-2α-methyl-5α-cholestane (20997-52-8,37163-88-5)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether; lithium / in fluessigem NH₃

2: pyridine

With pyridine; diethyl ether; lithium;

DOI:10.1021/ja01552a051

upstream raw materials:

2α-methyl-5α-cholestan-3β-ol

acetic anhydride

Cholest-4-en-3-one

dihydrocholesterone