(3R)-4-(Benzenesulfonyl)-2,3-dimethylbutan-2-ol

Base Information

Chemical Name:(3R)-4-(Benzenesulfonyl)-2,3-dimethylbutan-2-ol
CAS No.:93748-50-6
Molecular Formula:C12H18O3S
Molecular Weight:242.33452
Hs Code.:
DSSTox Substance ID:DTXSID60553401
Wikidata:Q82433977
Mol file:93748-50-6.mol

Synonyms:93748-50-6;(3R)-2,3-Dimethyl-4-(phenylsulfonyl)-2-butanol;(3R)-4-(Benzenesulfonyl)-2,3-dimethylbutan-2-ol;(R)-(-)-2,3-DIMETHYL-4-(PHENYLSULFONYL)-2-BUTANOL;SCHEMBL12398039;DTXSID60553401;AKOS025296422;(R)-4-Benzenesulfonyl-2,3-dimethyl-butan-2-ol

Suppliers and Price of (3R)-4-(Benzenesulfonyl)-2,3-dimethylbutan-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(3R)-2,3-Dimethyl-4-(phenylsulfonyl)-2-butanol
25mg
$ 165.00

Medical Isotopes, Inc.
(3R)-2,3-Dimethyl-4-(phenylsulfonyl)-2-butanol
250 mg
$ 2200.00

Medical Isotopes, Inc.
(3R)-2,3-Dimethyl-4-(phenylsulfonyl)-2-butanol
25 mg
$ 650.00

Crysdot
(3R)-2,3-Dimethyl-4-(phenylsulfonyl)-2-butanol 95+%
50mg
$ 421.00

Crysdot
(3R)-2,3-Dimethyl-4-(phenylsulfonyl)-2-butanol 95+%
250mg
$ 1265.00

Chemenu
(3R)-2,3-Dimethyl-4-(phenylsulfonyl)-2-butanol 95%
250mg
$ 1192.00

Alichem
(R)-(-)-2,3-dimethyl-4-(phenylsulfonyl)-2-butanol
250mg
$ 1313.25

Alichem
(R)-(-)-2,3-dimethyl-4-(phenylsulfonyl)-2-butanol
50mg
$ 433.50

Total 4 raw suppliers

Chemical Property of (3R)-4-(Benzenesulfonyl)-2,3-dimethylbutan-2-ol

Chemical Property:

PSA：62.75000
LogP:2.94810
Solubility.:Dichloromethane, Ethyl Acetate, Methanol
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:242.09766561
Heavy Atom Count:16
Complexity:308

Purity/Quality:

98% ^*data from raw suppliers

(3R)-2,3-Dimethyl-4-(phenylsulfonyl)-2-butanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CS(=O)(=O)C1=CC=CC=C1)C(C)(C)O
Isomeric SMILES:C[C@@H](CS(=O)(=O)C1=CC=CC=C1)C(C)(C)O
Uses R-2,3-DiMethyl-4-(phenylsulfonyl)-2-butanol is used in the preparation of Vitamin D2 derivatives.

Technology Process of (3R)-4-(Benzenesulfonyl)-2,3-dimethylbutan-2-ol

There total 11 articles about (3R)-4-(Benzenesulfonyl)-2,3-dimethylbutan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 93748-49-3
(R)-2,3-dimethyl-4-phenylthio-2-butanol

: 93748-50-6
(R)-2,3-dimethyl-4-phenylsulfonyl-2-butanol

Guidance literature:: With sodium tungstate; dihydrogen peroxide; at 70 ℃;
DOI:10.1016/S0040-4039(01)81381-2

Reference yield: 74.0%

: Toluene-4-sulfonic acid (R)-1,1,2-trimethyl-3-phenylsulfanyl-propyl ester

: 93748-50-6
(R)-2,3-dimethyl-4-phenylsulfonyl-2-butanol

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane;
DOI:10.1016/S0040-4039(00)61826-9

Reference yield:

: 73295-12-2
(S)-2,3-dimethyl-1,3-butanediol

: 93748-50-6
(R)-2,3-dimethyl-4-phenylsulfonyl-2-butanol

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / 2 h / Ambient temperature

2: potassium t-butoxide / dimethylformamide / 4 h / Ambient temperature

3: WO₃, 50percent NaOH, 30percent H₂O₂ / H₂O; ethanol / 0.67 h / 60 - 75 °C

With pyridine; sodium hydroxide; potassium tert-butylate; dihydrogen peroxide; tungsten(VI) oxide; In ethanol; water; N,N-dimethyl-formamide;
DOI:10.1246/bcsj.62.3132