6-Bromo-2-hydroxy-3-methoxybenzoic acid

Base Information

• Chemical Name: 6-Bromo-2-hydroxy-3-methoxybenzoic acid
• CAS No.: 35093-65-3
• Molecular Formula: C8H7BrO4
• Molecular Weight: 247.045
• Mol file: 35093-65-3.mol

Synonyms:6-Bromo-2-hydroxy-3-methoxybenzoic acid

Chemical Property of 6-Bromo-2-hydroxy-3-methoxybenzoic acid

Chemical Property:

• PSA: 66.76000
• LogP: 1.86150

Purity/Quality:

≥99% ^*data from raw suppliers

6-Bromo-2-hydroxy-3-methoxybenzoicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Bromo-2-hydroxy-3-methoxybenzoic acid

There total 3 articles about 6-Bromo-2-hydroxy-3-methoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-acetoxy-6-bromo-3-methoxy-benzoic acid methyl ester → 6-bromo-2-hydroxy-3-methoxy-benzoic acid (35093-65-3)

Guidance literature:

With sodium hydroxide;

DOI:10.1021/jo01184a001

Reference yield:

2-acetoxy-3-methoxy-benzoic acid methyl ester (500798-31-2) → 6-bromo-2-hydroxy-3-methoxy-benzoic acid (35093-65-3)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium acetate; acetic acid; bromine

2: aq.-ethanolic NaOH-solution

With sodium hydroxide; bromine; sodium acetate; acetic acid;

DOI:10.1021/jo01184a001

Reference yield:

6-bromo-2-hydroxy-3-methoxybenzaldehyde (20035-41-0) → 6-bromo-2-hydroxy-3-methoxy-benzoic acid (35093-65-3)

Guidance literature:

With sodium hydroxide; silver(l) oxide;

DOI:10.1016/0040-4020(72)84037-7

upstream raw materials:

6-bromo-2-hydroxy-3-methoxybenzaldehyde

2-acetoxy-3-methoxy-benzoic acid methyl ester

Downstream raw materials:

Isovanillic acid