(R)-5-BroMo-N,N-bis-(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-aMine

Base Information

Chemical Name:(R)-5-BroMo-N,N-bis-(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-aMine
CAS No.:877399-47-8
Molecular Formula:C23H26BrCl2FN2O5
Molecular Weight:580.278
Hs Code.:
Mol file:877399-47-8.mol

Synonyms:(R)-5-BroMo-N,N-bis-(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-aMine

Suppliers and Price of (R)-5-BroMo-N,N-bis-(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-aMine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(R)-5-Bromo-N,N-bis-(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine 98%
1g
$ 178.00

Chemenu
(R)-5-Bromo-N,N-bis-(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine 98%
1g
$ 168.00

Ambeed
(R)-5-Bromo-N,N-bis-(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine 98%
1g
$ 51.00

Ambeed
(R)-5-Bromo-N,N-bis-(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine 98%
250mg
$ 20.00

Ambeed
(R)-5-Bromo-N,N-bis-(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine 98%
100mg
$ 13.00

Alichem
(R)-5-Bromo-N,N-bis-(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
1g
$ 169.95

Abosyn
(R)-5-Bromo-N,N-bis-(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine 95-98%
1g
$ 315.00

Total 9 raw suppliers

Chemical Property of (R)-5-BroMo-N,N-bis-(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-aMine

Chemical Property:

PSA：77.96000
LogP:8.10660
Storage Temp.:2-8°C(protect from light)

Purity/Quality:

97% ^*data from raw suppliers

(R)-5-Bromo-N,N-bis-(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (R)-5-BroMo-N,N-bis-(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-aMine

There total 10 articles about (R)-5-BroMo-N,N-bis-(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-aMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1448326-33-7,877399-00-3
5-bromo-3-[1 (R)-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-pyridin-2-ylamine

: 24424-99-5
di-tert-butyl dicarbonate

: 877399-47-8
(R)-5-bromo-N,N-bis-(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridine-2-amine

Guidance literature:: dmap; In N,N-dimethyl-formamide; at 20 ℃; for 18h;

Reference yield: 85.0%

: C₂₃H₂₇Cl₂FN₂O₅

: 877399-47-8
(R)-5-bromo-N,N-bis-(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridine-2-amine

Guidance literature:: With N-Bromosuccinimide; In dichloromethane; at 0 ℃; for 1h; Temperature; Solvent;

Reference yield:

: 877397-70-1
(R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethyoxyl)-2-nitropyridine

: 877399-47-8
(R)-5-bromo-N,N-bis-(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridine-2-amine

Guidance literature:: Multi-step reaction with 3 steps

1: iron; hydrogenchloride / ethanol / 2.5 h / 90 °C

2: N-Bromosuccinimide / acetonitrile / 1.33 h / 0 °C

3: dmap; triethylamine / tetrahydrofuran / 70 °C

With hydrogenchloride; dmap; N-Bromosuccinimide; iron; triethylamine; In tetrahydrofuran; ethanol; acetonitrile;