Dehydro Barnidipine

Base Information

Chemical Name:Dehydro Barnidipine
CAS No.:172331-68-9
Molecular Formula:C₂₇H₂₇N₃O₆
Molecular Weight:489.528
Hs Code.:
Mol file:172331-68-9.mol

Synonyms:Dehydro Barnidipine;Methyl 2,6-DiMethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid (3S)-1-(PhenylMethyl)-3-pyrrolidinyl Ester

Suppliers and Price of Dehydro Barnidipine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
DehydroBarnidipine
50mg
$ 1540.00

TRC
DehydroBarnidipine
5mg
$ 195.00

Biosynth Carbosynth
Dehydro barnidipine
50 mg
$ 1911.00

Biosynth Carbosynth
Dehydro barnidipine
2 mg
$ 174.90

Biosynth Carbosynth
Dehydro barnidipine
25 mg
$ 1051.50

Biosynth Carbosynth
Dehydro barnidipine
10 mg
$ 578.20

Biosynth Carbosynth
Dehydro barnidipine
5 mg
$ 318.00

Total 6 raw suppliers

Chemical Property of Dehydro Barnidipine

Chemical Property:

PSA：114.55000
LogP:4.95260

Purity/Quality:

> 95% ^*data from raw suppliers

DehydroBarnidipine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses A metabolite of Barnidipine (B118700) in human plasma.

Technology Process of Dehydro Barnidipine

There total 10 articles about Dehydro Barnidipine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.6%

: 104713-75-9
barnidipine

: 172331-68-9
2,6-Dimethyl-4-(3-nitro-phenyl)-pyridine-3,5-dicarboxylic acid 3-((S)-1-benzyl-pyrrolidin-3-yl) ester 5-methyl ester

Guidance literature:: barnidipine; With hydrogenchloride; In water;

In water; at 20 ℃; for 6h;

Reference yield: 31.0%

: 104713-75-9
barnidipine

: 172331-68-9
3-(R)-1-benzylpyrrolidin-3-yl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate

Guidance literature:: With manganese(IV) oxide; In dichloromethane; at 20 ℃; for 720h; UV-irradiation;
DOI:10.3390/molecules19011344

Reference yield:

: 99-61-6
3-nitro-benzaldehyde

: 172331-68-9
3-(R)-1-benzylpyrrolidin-3-yl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate

Guidance literature:: Multi-step reaction with 7 steps

1: ammonium acetate / isopropyl alcohol / 15 h / 20 °C

2: methanol / 2 h / Reflux

3: sodium hydroxide / 1,2-dimethoxyethane / 2 h / 20 °C

4: cinchonine / water; N,N-dimethyl-formamide / 24 h / 20 - 120 °C

5: phosphorus pentachloride / dichloromethane / 1 h / 0 - 2 °C

6: 3 h / -15 °C

7: manganese(IV) oxide / dichloromethane / 720 h / 20 °C / UV-irradiation

With manganese(IV) oxide; phosphorus pentachloride; ammonium acetate; cinchonine; sodium hydroxide; In methanol; 1,2-dimethoxyethane; dichloromethane; water; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.3390/molecules19011344