17-Epimethyltestosterone

Base Information

• Chemical Name: 17-Epimethyltestosterone
• CAS No.: 2607-14-9
• Molecular Formula: C₂₀H₃₀O₂
• Molecular Weight: 302.457
• Hs Code.: 9999999999
• UNII: 5EL4L26MSF
• DSSTox Substance ID: DTXSID00427652
• Nikkaji Number: J490.678K
• Wikidata: Q27261924
• Mol file: 2607-14-9.mol

Synonyms:17 alpha Methyltestosterone;17 beta Hydroxy 17 methyl 4 androsten 3 one;17 beta Methyltestosterone;17 beta-Hydroxy-17-methyl-4-androsten-3-one;17 beta-Methyltestosterone;17 Epimethyltestosterone;17-alpha-Methyltestosterone;17-Epimethyltestosterone;17alpha Methyl Testosterone;17alpha Methyltestosterone;17alpha-Methyl-Testosterone;17alpha-Methyltestosterone;17beta Hydroxy 17 methyl 4 androsten 3 one;17beta Methyltestosterone;17beta-Hydroxy-17-methyl-4-androsten-3-one;17beta-Methyltestosterone;Android (Methyltestoterone);Android 10;Android 25;Android 5;Android-10;Android-25;Android-5;Mesteron;Mesterone;Metandren;Methitest;Methyltestosterone;Oreton;Testoviron;Testred;Virilon

Chemical Property of 17-Epimethyltestosterone

Chemical Property:

• Melting Point: 175-178°C
• Boiling Point: 434.4±45.0 °C(Predicted)
• PKA: 15.13±0.60(Predicted)
• PSA: 37.30000
• Density: 1.10±0.1 g/cm3(Predicted)
• LogP: 4.26930
• Storage Temp.: Refrigerator
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 302.224580195
• Heavy Atom Count: 22
• Complexity: 550

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC12CCC(=O)C=C1CCC3C2CCC4(C3CCC4(C)O)C
• Isomeric SMILES: C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@]4(C)O)C
• Uses: A new metabolite of 17α-Methyltestosterone (M326400).

Technology Process of 17-Epimethyltestosterone

There total 15 articles about 17-Epimethyltestosterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

methyltestosterone 17β-sulfate pyridinium salt (143579-42-4) → 17,17-dimethyl-18-norandrosta-4,13(14)-dien-3-one (1971-59-1) + 17α-hydroxy-17β-methylandrost-4-en-3-one (58-18-4,2826-09-7,6813-77-0,2607-14-9)

Guidance literature:

With phosphate buffer; Ambient temperature;

DOI:10.1016/0039-128X(92)90048-E

Reference yield:

→ 17β-hydroxy-17α-methyl-androst-4-en-3-one (58-18-4,2607-14-9,2826-09-7,6813-77-0)

Guidance literature:

β-Naphthol-Addukt C20H30O2*C10H8O, Ethylenchlorid, wss.NaOH;

Reference yield:

→ methyltestosterone (58-18-4,2607-14-9,2826-09-7,6813-77-0)

Guidance literature:

Dihydroxyandrosten VI, Oppenauer-Oxydation;

DOI:10.1016/0039-128X(78)90070-3

upstream raw materials:

17,20-epoxy-21-nor-pregn-4-en-3-one

17α-hydroxy-17β-methylandrost-5-en-3β-ol

cyclohexanone

Sulfuric acid mono-((8R,9S,10R,13S,14S,17S)-10,13,17-trimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl) ester

Downstream raw materials:

17-Methylene-4-androstene-3-one

17α-hydroxy-17β-methyl-5β-androstan-3-one

Refernces

• 1、 Schaenzer, Willi,Opfermann, Georg,Donike, Manfred. "17-Epimerization of 17α-methyl anabolic steroids in humans: metabolism and synthesis of 17α-hydroxy-17β-methyl steroids". . p. 537 - 550. Retrieved 2007/10/02.
• 2、 Els,Englert,Mueller,Fuerst. "On 9-beta, 10-alpha-steroids. 1. Preparation and properties of 6-halogen-9-beta,10-alpha-androstane derivatives". . p. 989 - 1001. Retrieved 2007/10/12.