Methyl (RS)-2-(aMinoMethyl)-3-phenylpropionate hydrochloride

Base Information

• Chemical Name: Methyl (RS)-2-(aMinoMethyl)-3-phenylpropionate hydrochloride
• CAS No.: 864182-43-4
• Molecular Formula: C11H16ClNO2
• Molecular Weight: 229.707
• Hs Code.: 2922499990
• Mol file: 864182-43-4.mol

Synonyms:Methyl (RS)-2-(aMinoMethyl)-3-phenylpropionate hydrochloride;Methyl (RS)-2-(aminomethyl)-3-phenylpropionate hydrochloride 97%

Chemical Property of Methyl (RS)-2-(aMinoMethyl)-3-phenylpropionate hydrochloride

Chemical Property:

• PSA: 52.32000
• LogP: 2.47930

Purity/Quality:

98%,99%, ^*data from raw suppliers

Methyl (RS)-2-(aminomethyl)-3-phenylpropionate hydrochloride 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl (RS)-2-(aMinoMethyl)-3-phenylpropionate hydrochloride

There total 1 articles about Methyl (RS)-2-(aMinoMethyl)-3-phenylpropionate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.6%

methyl (2Z)-2-cyano-3-phenyl acrylate (14533-85-8) → 2-aminomethyl-3-phenyl-propionic acid methyl ester hydrochloride (864182-43-4)

Guidance literature:

With hydrogenchloride; hydrogen; palladium(II) hydroxide/carbon; In water; at 20 ℃; for 72h; under 2585.81 Torr;

Reference yield: 63.3%

2-aminomethyl-3-phenyl-propionic acid methyl ester hydrochloride (864182-43-4) + 3-chloro-3-oxopropanoic acid methyl ester (37517-81-0) → 2-[(2-methoxycarbonyl-acetylamino)-methyl]-3-phenyl-propionic acid methyl ester (1005187-98-3)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 1.5h;

upstream raw materials:

methyl (2Z)-2-cyano-3-phenyl acrylate

Downstream raw materials:

2-[(2-methoxycarbonyl-acetylamino)-methyl]-3-phenyl-propionic acid methyl ester