JWH -210

Base Information

• Chemical Name: JWH -210
• CAS No.: 824960-64-7
• Molecular Formula: C₂₆H₂₇NO
• Molecular Weight: 369.506
• Mol file: 824960-64-7.mol

Synonyms:JWH -210;1-Pentyl-3-(4-ethyl-1-naphthoyl)indole;JWH-210,1-Pentyl-3-(4-ethyl-1-naphthoyl)indole;JWH 210 7-ethylnaphthyl isomer

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of JWH -210

Chemical Property:

• Boiling Point: 555.1±25.0 °C(Predicted)
• PSA: 22.00000
• Density: 1.07±0.1 g/cm3(Predicted)
• LogP: 6.77810

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: JWH 210 is a potent cannabimimetic alkylindole that has been identified in extracts from herbal blends. JWH 210 7-ethylnaphthyl isomer is a positional isomer of JWH 210, having the ethyl side chain at the 7 position rather than at the 4 position of the naphthyl group. The biological activities of this isomer have not been determined. This product is intended for forensic purposes.

Technology Process of JWH -210

There total 7 articles about JWH -210 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

→ (7-ethyl-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)methanone (824960-64-7)

Guidance literature:

Reference yield:

7-ethyl-1-naphthoyl chloride + 1-pentyl-1H-indole (59529-21-4) → (7-ethyl-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)methanone (824960-64-7)

Guidance literature:

With dimethylaluminum chloride; In hexane; dichloromethane; at 0 ℃; for 1h;

DOI:10.1016/j.bmc.2004.09.050

Reference yield:

1-acetyl-7-ethylnaphthalene (105523-17-9) → (7-ethyl-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)methanone (824960-64-7)

Guidance literature:

Multi-step reaction with 4 steps

1: iodine / 0.5 h / 100 °C

2: 65 percent / NaOH / H₂O / 2 h / Heating

3: thionyl chloride / 0.25 h / Heating

4: 0.1 g / Me₂AlCl / CH₂Cl₂; hexane / 1 h / 0 °C

With sodium hydroxide; thionyl chloride; iodine; dimethylaluminum chloride; In hexane; dichloromethane; water; 4: Friedel-Crafts reaction;

DOI:10.1016/j.bmc.2004.09.050

upstream raw materials:

1-pentyl-1H-indole

1-acetyl-7-ethylnaphthalene

2-ethylnaphthalene

7-ethyl-1-naphthoic acid