5-benzylamino-1,2,3,6-tetrahydropyridine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester

Base Information

Chemical Name:5-benzylamino-1,2,3,6-tetrahydropyridine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester
CAS No.:1293940-27-8
Molecular Formula:C₂₀H₂₈N₂O₄
Molecular Weight:360.453
Hs Code.:

Synonyms:5-benzylamino-1,2,3,6-tetrahydropyridine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester

Suppliers and Price of 5-benzylamino-1,2,3,6-tetrahydropyridine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 5-benzylamino-1,2,3,6-tetrahydropyridine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester

Chemical Property:

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

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Technology Process of 5-benzylamino-1,2,3,6-tetrahydropyridine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester

There total 3 articles about 5-benzylamino-1,2,3,6-tetrahydropyridine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.5%

: 71233-25-5
ethyl 1-tert-butoxycarbonyl-3-oxopiperidine-4-carboxylate

: 100-46-9
benzylamine

: 1293940-27-8
1-(tert-butyl) 4-ethyl 5-(benzylamino)-3,6-dihydropyridine-1,4(2H)-dicarboxylate

Guidance literature:: In toluene; for 72h; Reflux;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1293940-27-8
1-(tert-butyl) 4-ethyl 5-(benzylamino)-3,6-dihydropyridine-1,4(2H)-dicarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; hydrogen / 20% palladium hydroxide on carbon / ethanol / 24 h / 3102.97 Torr

2: toluene / 72 h / Reflux; Dean-Stark apparatus

With hydrogen; triethylamine; 20% palladium hydroxide on carbon; In ethanol; toluene;

Reference yield:

: 39514-19-7
ethyl 1-benzyl-3-oxo-4-piperidinecarboxylate

: 1293940-27-8
1-(tert-butyl) 4-ethyl 5-(benzylamino)-3,6-dihydropyridine-1,4(2H)-dicarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; hydrogen / 20% palladium hydroxide on carbon / ethanol / 24 h / 3102.97 Torr

2: toluene / 72 h / Reflux; Dean-Stark apparatus

With hydrogen; triethylamine; 20% palladium hydroxide on carbon; In ethanol; toluene;