SEP 174559 Hydrochloride

Base Information

• Chemical Name: SEP 174559 Hydrochloride
• CAS No.: 300701-71-7
• Molecular Formula: C₁₆H₁₅ClN₆O₃*ClH
• Molecular Weight: 411.247
• Mol file: 300701-71-7.mol

Synonyms:1-Piperazinecarboxylic Acid (5S)-6-(5-Chloro-2-pyridinyl)-6,7-dihydro-7-oxo- 5H-pyrrolo[3,4-b]pyrazin-5-yl Ester Hydrochloride;N-DeMethyl Eszopiclone Hydrochloride Salt;SEP 174559 Hydrochloride

Chemical Property of SEP 174559 Hydrochloride

Chemical Property:

• PSA: 100.55000
• LogP: 2.35950
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly), Water (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

N-DemethylEszopicloneHydrochlorideSalt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of SEP 174559 Hydrochloride

There total 2 articles about SEP 174559 Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

piperazine-1,4-dicarboxylic acid 1-chloro-ethyl ester 6-(5-chloro-pyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl ester → (S)-desmethylzopiclone hydrochloride (1216659-29-8,300701-71-7)

Guidance literature:

With methanol; In acetonitrile; Heating;

DOI:10.1016/S0957-4166(00)00455-9

Reference yield:

eszopiclone (138729-47-2) → (S)-desmethylzopiclone hydrochloride (1216659-29-8,300701-71-7)

Guidance literature:

Multi-step reaction with 2 steps

1: acetonitrile / 80 - 83 °C

2: MeOH / acetonitrile / Heating

With methanol; In acetonitrile;

DOI:10.1016/S0957-4166(00)00455-9

upstream raw materials:

eszopiclone