4-aMino-N-(4-(2-aMino-6-MethylpyriMidin-4-ylaMino)phenyl)benzaMide

Base Information

Chemical Name:4-aMino-N-(4-(2-aMino-6-MethylpyriMidin-4-ylaMino)phenyl)benzaMide
CAS No.:1020150-22-4
Molecular Formula:C18H18N6O
Molecular Weight:334.381
Hs Code.:
Mol file:1020150-22-4.mol

Synonyms:4-aMino-N-(4-(2-aMino-6-MethylpyriMidin-4-ylaMino)phenyl)benzaMide

Suppliers and Price of 4-aMino-N-(4-(2-aMino-6-MethylpyriMidin-4-ylaMino)phenyl)benzaMide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Amino-N-(4-((2-amino-6-methylpyrimidin-4-yl)amino)phenyl)benzamide 95%
250mg
$ 980.00

Chemenu
4-Amino-N-(4-((2-amino-6-methylpyrimidin-4-yl)amino)phenyl)benzamide 95%
250mg
$ 916.00

Alichem
4-Amino-N-(4-((2-amino-6-methylpyrimidin-4-yl)amino)phenyl)benzamide
250mg
$ 989.80

Total 5 raw suppliers

Chemical Property of 4-aMino-N-(4-(2-aMino-6-MethylpyriMidin-4-ylaMino)phenyl)benzaMide

Chemical Property:

PSA：118.95000
LogP:4.25370

Purity/Quality:

97% ^*data from raw suppliers

4-Amino-N-(4-((2-amino-6-methylpyrimidin-4-yl)amino)phenyl)benzamide 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-aMino-N-(4-(2-aMino-6-MethylpyriMidin-4-ylaMino)phenyl)benzaMide

There total 5 articles about 4-aMino-N-(4-(2-aMino-6-MethylpyriMidin-4-ylaMino)phenyl)benzaMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1020087-05-1
N-[4-(2-amino-6-methylpyrimidin-4-ylamino)phenyl]-4-nitrobenzamide

: 1020150-22-4
4-amino-N-[4-(2-amino-6-methylpyrimidin-4-ylamino)phenyl]benzamide

Guidance literature:: With decaborane; palladium 10% on activated carbon; acetic acid; In methanol; for 2h; Inert atmosphere; Reflux;
DOI:10.1016/j.bmcl.2013.01.085

Reference yield:

: 100-01-6,104810-17-5
4-nitro-aniline

: 1020150-22-4
4-amino-N-[4-(2-amino-6-methylpyrimidin-4-ylamino)phenyl]benzamide

Guidance literature:: Multi-step reaction with 4 steps

1: palladium diacetate; potassium carbonate; XPhos / tert-butyl alcohol; water / 1.5 h / 110 °C / Sealed tube; Inert atmosphere

2: hydrogen / ethanol / 24 h / Inert atmosphere

3: caesium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C / Inert atmosphere

4: acetic acid; decaborane; palladium 10% on activated carbon / methanol / 2 h / Inert atmosphere; Reflux

With decaborane; palladium 10% on activated carbon; hydrogen; palladium diacetate; potassium carbonate; caesium carbonate; acetic acid; XPhos; In methanol; ethanol; water; N,N-dimethyl-formamide; tert-butyl alcohol; 1: |Buchwald-Hartwig Coupling;
DOI:10.1016/j.bmcl.2013.01.085

Reference yield:

: 20719-42-0
6-methyl-N⁴-(4-nitrophenyl)-2,4-diamino-pyrimidine

: 1020150-22-4
4-amino-N-[4-(2-amino-6-methylpyrimidin-4-ylamino)phenyl]benzamide

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogen / ethanol / 24 h / Inert atmosphere

2: caesium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C / Inert atmosphere

3: acetic acid; decaborane; palladium 10% on activated carbon / methanol / 2 h / Inert atmosphere; Reflux

With decaborane; palladium 10% on activated carbon; hydrogen; caesium carbonate; acetic acid; In methanol; ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2013.01.085