Mevastatin hydroxy acid sodium

Base Information

• Chemical Name: Mevastatin hydroxy acid sodium
• CAS No.: 99782-89-5
• Molecular Formula: C23H35NaO6
• Molecular Weight: 430.51017
• UNII: F346G86K5B
• ChEMBL ID: CHEMBL519723
• DSSTox Substance ID: DTXSID40587906
• Nikkaji Number: J452.042D
• Wikidata: Q27277566
• Mol file: 99782-89-5.mol

Synonyms:99782-89-5;Mevastatin hydroxy acid sodium;Mevastatin Hydroxy Acid Sodium Salt;Mevastatin Sodium;ML 236B Sodium Salt;Mevastatin Acid Sodium Salt;F346G86K5B;sodium;(3R,5R)-7-[(1S,2S,8S,8aR)-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate;UNII-F346G86K5B;CHEMBL519723;DTXSID40587906;Q27277566;1-NAPHTHALENEHEPTANOIC ACID, 1,2,6,7,8,8A-HEXAHYDRO-.BETA.,.DELTA.-DIHYDROXY-2-METHYL-8-((2S)-2-METHYL-1-OXOBUTOXY)-, SODIUM SALT (1:1), (.BETA.R,.DELTA.R,1S,2S,8S,8AR)-;1-NAPHTHALENEHEPTANOIC ACID, 1,2,6,7,8,8A-HEXAHYDRO-.BETA.,.DELTA.-DIHYDROXY-2-METHYL-8-(2-METHYL-1-OXOBUTOXY)-, MONOSODIUM SALT, (1S-(1.ALPHA.(.BETA.S*,.DELTA.S*),2.ALPHA.,8.BETA.(R*),8A.ALPHA.))-;1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta-dihydroxy-2-methyl-8-((2S)-2-methyl-1-oxobutoxy)-, sodium salt (1:1), (betaR,deltaR,1S,2S,8S,8aR)-;1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta-dihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, monosodium salt, (1S-(1alpha(betaS*,deltaS*),2alpha,8beta(R*),8aalpha))-;Sodium (3R,5R)-3,5-dihydroxy-7-[(1S,2S,8S,8aR)-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoate

Chemical Property of Mevastatin hydroxy acid sodium

Chemical Property:

• PSA: 83.83000
• LogP: 3.58390
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 11
• Exact Mass: 430.23313311
• Heavy Atom Count: 30
• Complexity: 631

Purity/Quality:

98% ^*data from raw suppliers

MevastatinHydroxyAcidSodiumSalt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCC(C)C(=O)OC1CCC=C2C1C(C(C=C2)C)CCC(CC(CC(=O)[O-])O)O.[Na+]
• Isomeric SMILES: CC[C@H](C)C(=O)O[C@H]1CCC=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)[O-])O)O.[Na+]
• Uses: An active carboxylate of Mevastatin (M340500). It is a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase with hypocholesterolemic activity. It has been shown to be effective in reducing cholesterol synthesis in vivo, and thereby in lowering cholesterol levels in blood.