Pyridine, 4-(5-((1R)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4H-1,2,4-triazol-3-yl)-

Base Information

Chemical Name:Pyridine, 4-(5-((1R)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4H-1,2,4-triazol-3-yl)-
CAS No.:934282-55-0
Molecular Formula:C19H16ClN5O2
Molecular Weight:381.821
Hs Code.:
European Community (EC) Number:642-444-3
UNII:MQ908Y1ZB2
ChEMBL ID:CHEMBL3545164
Metabolomics Workbench ID:153594
Nikkaji Number:J3.560.339E
Wikidata:Q27284176
Mol file:934282-55-0.mol

Synonyms:AZD2066

Suppliers and Price of Pyridine, 4-(5-((1R)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4H-1,2,4-triazol-3-yl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
AZD2066
1mg
$ 125.00

Tocris
AZD2066 ≥98%(HPLC)
10
$ 212.00

ChemScene
AZD2066 >99.0%
5mg
$ 585.00

Total 5 raw suppliers

Chemical Property of Pyridine, 4-(5-((1R)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4H-1,2,4-triazol-3-yl)-

Chemical Property:

Boiling Point:626.3±65.0 °C(Predicted)
PKA:1.91±0.10(Predicted)
PSA：78.86000
Density:1.39±0.1 g/cm3(Predicted)
LogP:4.32550
Storage Temp.:-20°C Freezer, Under inert atmosphere
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:381.0992525
Heavy Atom Count:27
Complexity:481

Purity/Quality:

97% ^*data from raw suppliers

AZD2066 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=NOC(=C1)C2=CC(=CC=C2)Cl)OC3=NN=C(N3C)C4=CC=NC=C4
Isomeric SMILES:C[C@H](C1=NOC(=C1)C2=CC(=CC=C2)Cl)OC3=NN=C(N3C)C4=CC=NC=C4
Recent ClinicalTrials:Study to Evaluate the Analgesic Efficacy of 28 Days' Oral Administration of AZD2066 Compared With Placebo in Patients With Painful Diabetic Neuropathy
Uses AZD 2066 is a mGluR5 anatagonist that is used for treating and preventing pain, neurological, psychiatric and other diseases.

Technology Process of Pyridine, 4-(5-((1R)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4H-1,2,4-triazol-3-yl)-

There total 2 articles about Pyridine, 4-(5-((1R)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4H-1,2,4-triazol-3-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%