2-Cyclopenten-1-one, 3-(3-hydroxy-1-propynyl)-2-methyl- (9CI)

Base Information

Chemical Name:2-Cyclopenten-1-one, 3-(3-hydroxy-1-propynyl)-2-methyl- (9CI)
CAS No.:81280-45-7
Molecular Formula:C₉H₁₀O₂
Molecular Weight:150.177
Hs Code.:
Mol file:81280-45-7.mol

Synonyms:2-Cyclopenten-1-one, 3-(3-hydroxy-1-propynyl)-2-methyl- (9CI)

Suppliers and Price of 2-Cyclopenten-1-one, 3-(3-hydroxy-1-propynyl)-2-methyl- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Cyclopenten-1-one, 3-(3-hydroxy-1-propynyl)-2-methyl- (9CI)

Chemical Property:

PSA：37.30000
LogP:0.66150

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Cyclopenten-1-one, 3-(3-hydroxy-1-propynyl)-2-methyl- (9CI)

There total 2 articles about 2-Cyclopenten-1-one, 3-(3-hydroxy-1-propynyl)-2-methyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 765-69-5
2-Methylcyclopentane-1,3-dione

: 81280-45-7
3-(3-hydroxyprop-1-ynyl)-2-methylcyclopent-2-en-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / triphenylphosphine, iodine, triethylamine / acetonitrile / 18 h / Ambient temperature

2: 1.) copper(I) chloride, aq. ammonia; 3.) toluene-4-sulphonic acid / 1) ethanol, room temperature, 1 h; 2) DMF, 125 deg C, 5 h; 3) methanol, 24 h, room temperature

With ammonium hydroxide; iodine; toluene-4-sulfonic acid; triethylamine; triphenylphosphine; copper(l) chloride; In acetonitrile;
DOI:10.1039/P19810003234

Reference yield:

: 6089-04-9
3-(tetrahydropyran-2'-yloxy)propyne

: 56778-49-5
3-iodo-2-methyl-2-cyclopentenone

: 81280-45-7
3-(3-hydroxyprop-1-ynyl)-2-methylcyclopent-2-en-1-one

Guidance literature:: With ammonium hydroxide; toluene-4-sulfonic acid; copper(l) chloride; Yield given. Multistep reaction; 1) ethanol, room temperature, 1 h; 2) DMF, 125 deg C, 5 h; 3) methanol, 24 h, room temperature;
DOI:10.1039/P19810003234

Reference yield:

: 81280-45-7
3-(3-hydroxyprop-1-ynyl)-2-methylcyclopent-2-en-1-one

: 345620-19-1,81280-52-6
E-triphenylphosphonium 4-<3-(2-methyl-3-oxocyclopent-1-enyl)bicyclo<2.2.1>hepta-2,5-dien-2-yl>-2-oxobut-2-enylide

Guidance literature:: Multi-step reaction with 3 steps

1: pyridinium chlorochromate / CH₂Cl₂ / 3 h

2: 38 percent / CH₂Cl₂; diethyl ether / 20 h / Ambient temperature

3: 1.) potassium t-butoxide / 1) DMSO, room temperature, 1 h; 2) 18 h

With potassium tert-butylate; pyridinium chlorochromate; In diethyl ether; dichloromethane;
DOI:10.1039/P19810003234