4H-Pyrazolo(3,4-d)pyrimidin-4-one, 1,5-dihydro-5-amino-6-((2-chlorophenyl)amino)-

Base Information

Chemical Name:4H-Pyrazolo(3,4-d)pyrimidin-4-one, 1,5-dihydro-5-amino-6-((2-chlorophenyl)amino)-
CAS No.:141300-22-3
Molecular Formula:C11H9 Cl N6 O
Molecular Weight:276.6818
Hs Code.:
DSSTox Substance ID:DTXSID60161666
Nikkaji Number:J475.952D
Wikidata:Q83030110
Mol file:141300-22-3.mol

Synonyms:BRN 4878072;4H-Pyrazolo(3,4-d)pyrimidin-4-one, 1,5-dihydro-5-amino-6-((2-chlorophenyl)amino)-;141300-22-3;1,5-Dihydro-5-amino-6-((2-chlorophenyl)amino)-4H-pyrazolo(3,4-d)pyrimidin-4-one;DTXSID60161666;LS-129286

Suppliers and Price of 4H-Pyrazolo(3,4-d)pyrimidin-4-one, 1,5-dihydro-5-amino-6-((2-chlorophenyl)amino)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4H-Pyrazolo(3,4-d)pyrimidin-4-one, 1,5-dihydro-5-amino-6-((2-chlorophenyl)amino)-

Chemical Property:

Vapor Pressure:3.23E-12mmHg at 25°C
Boiling Point:551.7°Cat760mmHg
Flash Point:287.5°C
PSA：104.85000
Density:1.75g/cm³
LogP:1.23350
XLogP3:0.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:276.0526366
Heavy Atom Count:19
Complexity:403

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)NC2=NC3=C(C=NN3)C(=O)N2N)Cl

Technology Process of 4H-Pyrazolo(3,4-d)pyrimidin-4-one, 1,5-dihydro-5-amino-6-((2-chlorophenyl)amino)-

There total 2 articles about 4H-Pyrazolo(3,4-d)pyrimidin-4-one, 1,5-dihydro-5-amino-6-((2-chlorophenyl)amino)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 141300-14-3,958386-51-1
5-[3-(2-Chloro-phenyl)-thioureido]-1H-pyrazole-4-carboxylic acid ethyl ester

: 141300-22-3
5-Amino-6-(2-chloro-phenylamino)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one

Guidance literature:: With hydrazine hydrate; In ethanol; for 8h; Heating;
DOI:10.1016/0223-5234(92)90064-8

Reference yield:

: 2740-81-0
2-chlorophenylisothiocyanate

: 141300-22-3
5-Amino-6-(2-chloro-phenylamino)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 50 percent / toluene / 6 h / Heating

2: 90 percent / NH₂NH₂*H₂O / ethanol / 8 h / Heating

With hydrazine hydrate; In ethanol; toluene;
DOI:10.1016/0223-5234(92)90064-8