1H-Pyrrolo[2,3-b]pyridine, 1-acetyl-2,3-dihydro-4,6-dimethyl- (9CI)

Base Information

Chemical Name:1H-Pyrrolo[2,3-b]pyridine, 1-acetyl-2,3-dihydro-4,6-dimethyl- (9CI)
CAS No.:698973-92-1
Molecular Formula:C₁₁H₁₄N₂O
Molecular Weight:190.245
Hs Code.:
Mol file:698973-92-1.mol

Synonyms:1H-Pyrrolo[2,3-b]pyridine, 1-acetyl-2,3-dihydro-4,6-dimethyl- (9CI)

Suppliers and Price of 1H-Pyrrolo[2,3-b]pyridine, 1-acetyl-2,3-dihydro-4,6-dimethyl- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1H-Pyrrolo[2,3-b]pyridine, 1-acetyl-2,3-dihydro-4,6-dimethyl- (9CI)

Chemical Property:

Melting Point:105 °C (ethyl acetate)
PSA：33.20000
LogP:1.67240

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 1H-Pyrrolo[2,3-b]pyridine, 1-acetyl-2,3-dihydro-4,6-dimethyl- (9CI)

There total 3 articles about 1H-Pyrrolo[2,3-b]pyridine, 1-acetyl-2,3-dihydro-4,6-dimethyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 699003-02-6
2-[N-acetyl-N-(pent-3-ynyl)amino]-4,6-dimethylpyrimidine

: 698973-92-1
1-acetyl-4,6-dimethyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: In diphenylether; at 250 ℃; for 10h;
DOI:10.1021/jo048842u

Reference yield:

: 154499-80-6
4,6-dimethylpyrimidin-2-yl trifluoromethanesulfonate

: 698973-92-1
1-acetyl-4,6-dimethyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 57 percent / Et₃N / dimethylformamide / 24 h / 20 °C

2: DMAP / 20 h / 100 °C

3: 82 percent / diphenyl ether / 10 h / 250 °C

With dmap; triethylamine; In diphenylether; N,N-dimethyl-formamide; 3: Van der Plas reaction;
DOI:10.1021/jo048842u

Reference yield:

: 698973-84-1
4,6-dimethyl-2-(pent-3-ynylamino)pyrimidine

: 698973-92-1
1-acetyl-4,6-dimethyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: DMAP / 20 h / 100 °C

2: 82 percent / diphenyl ether / 10 h / 250 °C

With dmap; In diphenylether; 2: Van der Plas reaction;
DOI:10.1021/jo048842u