1-Benzyl-6-hydroxy-7-cyano-5-azaindolin

Base Information

Chemical Name:1-Benzyl-6-hydroxy-7-cyano-5-azaindolin
CAS No.:66751-31-3
Molecular Formula:C₁₅H₁₃N₃O
Molecular Weight:251.288
Hs Code.:2933990090
DSSTox Substance ID:DTXSID50353619
Wikidata:Q82131318
ChEMBL ID:CHEMBL1307062

Synonyms:66751-31-3;1-BENZYL-6-HYDROXY-7-CYANO-5-AZAINDOLIN;1-Benzyl-6-hydroxy-2,3-dihydro-1H-pyrrolo[3,2-c]pyridine-7-carbonitrile;1-benzyl-6-oxo-3,5-dihydro-2H-pyrrolo[3,2-c]pyridine-7-carbonitrile;1-Benzyl-6-hydroxy-1h,2h,3h-pyrrolo[3,2-c]pyridine-7-carbonitrile;1-benzyl-6-oxo-2,3,5,6-tetrahydro-1H-pyrrolo[3,2-c]pyridine-7-carbonitrile;SMR000113380;MLS000549945;CHEMBL1307062;DTXSID50353619;HMS2307K21;1-benzyl-6-hydroxy-7-cyano-5-azaindoline;CS-0242186;EN300-245845;AH-262/01737039

Suppliers and Price of 1-Benzyl-6-hydroxy-7-cyano-5-azaindolin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 1-Benzyl-6-hydroxy-7-cyano-5-azaindolin

Chemical Property:

PSA：60.15000
LogP:2.28658
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:251.105862047
Heavy Atom Count:19
Complexity:503

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(C2=C(C(=O)NC=C21)C#N)CC3=CC=CC=C3

Technology Process of 1-Benzyl-6-hydroxy-7-cyano-5-azaindolin

There total 4 articles about 1-Benzyl-6-hydroxy-7-cyano-5-azaindolin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 78394-65-7
1-Benzyl-6-methoxy-7-cyano-5-azaindoline

: 66751-31-3
1-benzyl-6-hydroxy-7-cyano-5-azaindoline

Guidance literature:: With hydrogenchloride; In methanol; for 15h; Heating;
DOI:10.1007/BF00506995

Reference yield: 33.0%

: 1-Benzyl-6-(3-isopropyl-2-phenyl-oxazolidin-5-ylmethoxy)-2,3-dihydro-1H-pyrrolo[3,2-c]pyridine-7-carbonitrile

: 66751-31-3
1-benzyl-6-hydroxy-7-cyano-5-azaindoline

: 84905-89-5
1-Benzyl-6-(3'-isopropylamino-2'-hydroxypropoxy)-7-cyano-5-azaindoline

Guidance literature:: In toluene; at 50 ℃; for 2h; pH: 3.0;
DOI:10.1007/BF00770316

Reference yield:

: 66751-32-4
1-benzyl-6-chloro-7-cyano-5-azaindoline

: 66751-31-3
1-benzyl-6-hydroxy-7-cyano-5-azaindoline

Guidance literature:: Multi-step reaction with 2 steps

1: KOH / 18-crown-6 / toluene / 5 h / Heating

2: 33 percent / toluene / 2 h / 50 °C / pH: 3.0

With potassium hydroxide; 18-crown-6 ether; In toluene;
DOI:10.1007/BF00770316