Methyl phenylalanylmethioninate

Base Information

Chemical Name:Methyl phenylalanylmethioninate
CAS No.:22248-60-8
Molecular Formula:C15H22N2O3S
Molecular Weight:310.417
Hs Code.:
DSSTox Substance ID:DTXSID20512377
Mol file:22248-60-8.mol

Synonyms:Methyl phenylalanylmethioninate;methyl 2-[(2-amino-3-phenylpropanoyl)amino]-4-methylsulfanylbutanoate;22248-60-8;DTXSID20512377

Suppliers and Price of Methyl phenylalanylmethioninate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(S,S)-2-(2-AMINO-3-PHENYL-PROPIONYLAMINO)-4-METHYLSULFANYL-BUTYRIC ACID METHYL ESTER 95.00%
1G
$ 982.33

Total 6 raw suppliers

Chemical Property of Methyl phenylalanylmethioninate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:518.818°C at 760 mmHg
Flash Point:267.572°C
PSA：106.72000
Density:1.169g/cm³
LogP:2.05850
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:310.13511374
Heavy Atom Count:21
Complexity:333

Purity/Quality:

97% ^*data from raw suppliers

(S,S)-2-(2-AMINO-3-PHENYL-PROPIONYLAMINO)-4-METHYLSULFANYL-BUTYRIC ACID METHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C(CCSC)NC(=O)C(CC1=CC=CC=C1)N

Technology Process of Methyl phenylalanylmethioninate

There total 6 articles about Methyl phenylalanylmethioninate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 40290-63-9
Methyl ester of N-t-butyloxycarbonyl-L-phenylalanyl-L-methionine

: 22248-60-8
L-phenylalanyl-L-methionine methyl ester

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h; Inert atmosphere;
DOI:10.1002/anie.201809400

Reference yield:

: 2491-18-1
(S)-methyl 2-amino-4-(methylthio)butanoate hydrochloride

: 22248-60-8
L-phenylalanyl-L-methionine methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: N-methylmorpholine / CH₂Cl₂; dimethylformamide / 1.) 0 deg C, 1 h, 2.) to r. t., 1 h

2: HCl / methanol / 2 h

With 4-methyl-morpholine; hydrogenchloride; In methanol; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 13734-34-4
N-tert-butoxycarbonyl-L-phenylalanine

: 22248-60-8
L-phenylalanyl-L-methionine methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide

2: HCl /acetic acid/ anisole / 1.5 h

With hydrogenchloride; benzotriazol-1-ol; acetic acid; methoxybenzene; triethylamine; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide;