Fluoroatorvastatin

Base Information

Chemical Name:Fluoroatorvastatin
CAS No.:693794-20-6
Molecular Formula:C66H66CaF4N4O10
Molecular Weight:1191.3226528
Hs Code.:
European Community (EC) Number:823-242-6
UNII:MOS10V5E5M
DSSTox Substance ID:DTXSID20219470
Wikidata:Q27284147
Mol file:693794-20-6.mol

Synonyms:Fluoroatorvastatin;Difluoro Atorvastatin;693794-20-6;UNII-MOS10V5E5M;MOS10V5E5M;(3R,5R)-7-(2,3-Bis(4-fluorophenyl)-5-(1-methylethyl)-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid;Atorvastatin calcium trihydrate impurity C [EP];1H-Pyrrole-1-heptanoic acid, 2,3-bis(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-4-((phenylamino)carbonyl)-, (betaR,deltaR);Atorvastatin IMpurity C;SCHEMBL6764100;DTXSID20219470;(3R,5R)-7-(2,3-bis(4-fluorophenyl)-5-isopropyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid;(3R,5R)-7-[2,3-bis(4-fluorophenyl)-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid;HY-135151;CS-0109630;F19275;ATORVASTATIN CALCIUM IMPURITY C [EP IMPURITY];Q27284147;1H-PYRROLE-1-HEPTANOIC ACID, 2,3-BIS(4-FLUOROPHENYL)-.BETA.,.DELTA.-DIHYDROXY-5-(1-METHYLETHYL)-4-((PHENYLAMINO)CARBONYL)-, (.BETA.R,.DELTA.R)

Suppliers and Price of Fluoroatorvastatin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Biosynth Carbosynth
Difluoro atorvastatin
50 mg
$ 1529.00

Biosynth Carbosynth
Difluoro atorvastatin
25 mg
$ 841.00

Biosynth Carbosynth
Difluoro atorvastatin
10 mg
$ 462.50

Biosynth Carbosynth
Difluoro atorvastatin
5 mg
$ 254.40

Biosynth Carbosynth
Difluoro atorvastatin
2 mg
$ 139.90

Total 8 raw suppliers

Chemical Property of Fluoroatorvastatin

Chemical Property:

Boiling Point:720.7±60.0 °C(Predicted)
PKA:4.29±0.10(Predicted)
PSA：115.28000
Density:1.26±0.1 g/cm3(Predicted)
LogP:6.83670
XLogP3:5.1
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:12
Exact Mass:576.24357851
Heavy Atom Count:42
Complexity:855

Purity/Quality:

97% ^*data from raw suppliers

Difluoro atorvastatin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)O)O)O)C2=CC=C(C=C2)F)C3=CC=C(C=C3)F)C(=O)NC4=CC=CC=C4
Isomeric SMILES:CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)O)O)O)C2=CC=C(C=C2)F)C3=CC=C(C=C3)F)C(=O)NC4=CC=CC=C4
Uses Atorvastatin impurity.

Technology Process of Fluoroatorvastatin

There total 1 articles about Fluoroatorvastatin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: