17-Acetoxy-6-chloro-3-ethoxypregna-3,5-diene-20-one

Base Information

• Chemical Name: 17-Acetoxy-6-chloro-3-ethoxypregna-3,5-diene-20-one
• CAS No.: 4809-88-5
• Molecular Formula: C₂₅H₃₅ClO₄
• Molecular Weight: 435.003
• Mol file: 4809-88-5.mol

Synonyms:17-Acetoxy-6-chloro-3-ethoxypregna-3,5-diene-20-one;17α-Acetoxy-6-chloro-3-ethoxypregna-3,5-dien-20-one

Chemical Property of 17-Acetoxy-6-chloro-3-ethoxypregna-3,5-diene-20-one

Chemical Property:

• Melting Point: 180 °C
• PSA: 52.60000
• LogP: 5.93690

Purity/Quality:

17-Acetoxy-6-chloro-3-ethoxypregna-3,5-dien-20-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 17-Acetoxy-6-chloro-3-ethoxypregna-3,5-dien-20-one is an impurity of Chlormadinone (C343500), an orally active progesteron with antiandrogenic activity; has been used in combinations as an oral contraceptive.

Technology Process of 17-Acetoxy-6-chloro-3-ethoxypregna-3,5-diene-20-one

There total 4 articles about 17-Acetoxy-6-chloro-3-ethoxypregna-3,5-diene-20-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Acetic acid (R)-17-acetyl-6-chloro-3-ethoxy-10,13-dimethyl-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl ester (4203-01-4,4809-88-5)

Guidance literature:

5,6-Dichlor-17α-acetoxy-pregnan-3,20-dion, Orthoameisensaeure-aethylester/Toluol-sulfonsaeure;

Reference yield:

→ Acetic acid (10S,13S,17R)-17-acetyl-6-chloro-3-ethoxy-10,13-dimethyl-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl ester (4203-01-4,4809-88-5)

Guidance literature:

Pregnen-dion VIII, HC(OEt)3 u. TosOH V;

Reference yield:

→ 6-Chlor-3-ethoxy-3,5-pregnadion-17α-ol-20-on-17-acetat (4203-01-4,4809-88-5)

Guidance literature:

entspr. 3-on-Verb., HC(OEt)3;

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