3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine

Base Information

• Chemical Name: 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine
• CAS No.: 854601-60-8
• Molecular Formula: C23H49NO11
• Molecular Weight: 515.642
• Mol file: 854601-60-8.mol

Synonyms:3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine;m-PEG11-amine

Chemical Property of 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine

Chemical Property:

• Boiling Point: 551.9±45.0 °C(Predicted)
• PKA: 8.74±0.10(Predicted)
• PSA: 127.55000
• Density: 1.070±0.06 g/cm3(Predicted)
• LogP: 0.45780

Purity/Quality:

99.3% ^*data from raw suppliers

2,5,8,11,14,17,20,23,26,29,32-Undecaoxatetratriacontan-34-amine min.95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: m-PEG11-amine is a water soluble PEG linker containing an amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media.

Technology Process of 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine

There total 3 articles about 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C31H51NO13 → 2,5,8,11,14,17,20,23,26,29,32-undecaoxatetratriacontan-34-amine (854601-60-8)

Guidance literature:

With hydrazine; In tetrahydrofuran; water; at 20 ℃; for 4h;

DOI:10.1002/chem.202102049

Reference yield:

2,5,8,11,14,17,20,23,26,29,32-undecaoxatetratriacontan-34-yl 4-methylbenzenesulfonate → 2,5,8,11,14,17,20,23,26,29,32-undecaoxatetratriacontan-34-amine (854601-60-8)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 12 h / Reflux

2: hydrazine / tetrahydrofuran; water / 4 h / 20 °C

With potassium carbonate; hydrazine; In tetrahydrofuran; water; acetonitrile;

DOI:10.1002/chem.202102049

Reference yield:

C24H50O12 → 2,5,8,11,14,17,20,23,26,29,32-undecaoxatetratriacontan-34-amine (854601-60-8)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridine / -5 - 0 °C

2: potassium carbonate / acetonitrile / 12 h / Reflux

3: hydrazine / tetrahydrofuran; water / 4 h / 20 °C

With pyridine; potassium carbonate; hydrazine; In tetrahydrofuran; water; acetonitrile;

DOI:10.1002/chem.202102049

Downstream raw materials:

CH₃(OCH₂CH₂)11-NH-13-cis-retinamide

Refernces