3-(TrifluoroMethyl)-3-phenyldiaziridine

Base Information

Chemical Name:3-(TrifluoroMethyl)-3-phenyldiaziridine
CAS No.:40618-96-0
Molecular Formula:C8H7F3N2
Molecular Weight:188.152
Hs Code.:
Mol file:40618-96-0.mol

Synonyms:3-(TrifluoroMethyl)-3-phenyldiaziridine;3-Phenyl-3-(trifluoroMethyl)-diaziridine;Diaziridine, 3-phenyl-3-(trifluoroMethyl)-

Suppliers and Price of 3-(TrifluoroMethyl)-3-phenyldiaziridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Phenyl-3-(trifluoromethyl)-diaziridine
50mg
$ 140.00

Medical Isotopes, Inc.
3-Phenyl-3-(trifluoromethyl)-diaziridine
50 mg
$ 625.00

American Custom Chemicals Corporation
3-PHENYL-3-(TRIFLUOROMETHYL)DIAZIRIDINE 95.00%
50MG
$ 721.88

Total 2 raw suppliers

Chemical Property of 3-(TrifluoroMethyl)-3-phenyldiaziridine

Chemical Property:

PSA：43.88000
LogP:2.16710
Solubility.:Chloroform, Dichloromethane, Diethyl Ether, Ethyl Acetate

Purity/Quality:

99%+ ^*data from raw suppliers

3-Phenyl-3-(trifluoromethyl)-diaziridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 3-Phenyl-3-(trifluoromethyl)-diaziridine is intermediate in the synthesis of a diazirine photophore useful in photoaffinity labelling.

Technology Process of 3-(TrifluoroMethyl)-3-phenyldiaziridine

There total 7 articles about 3-(TrifluoroMethyl)-3-phenyldiaziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 40618-87-9
C₁₅H₁₂F₃NO₃S

: 40618-96-0
3-phenyl-3-(trifluoromethyl)diaziridine

Guidance literature:: With ammonia; In diethyl ether; at -78 ℃; for 18h; Sealed tube; Inert atmosphere;
DOI:10.1021/acs.orglett.1c01750

Reference yield: 82.0%

: C₈H₅F₃NO₃PolS

: 40618-96-0
3-phenyl-3-(trifluoromethyl)diaziridine

Guidance literature:: With ammonia; In 1,4-dioxane; at 20 ℃; for 12h; sulfonyl oxime resin
DOI:10.1021/acs.orglett.6b03252

Reference yield:

: 434-45-7
2,2,2-Trifluoroacetophenone

: 40618-96-0
3-phenyl-3-(trifluoromethyl)diaziridine

Guidance literature:: Multi-step reaction with 3 steps

1.1: pyridine; hydroxylamine hydrochloride / 2 h / 0 - 70 °C

2.1: triethylamine / acetone / 0.25 h / 0 °C

2.2: 3 h

3.1: ammonia / diethyl ether / 2 h / -78 °C / Inert atmosphere

With pyridine; hydroxylamine hydrochloride; ammonia; triethylamine; In diethyl ether; acetone;