Methyl4,6-O-benzylidene-3-deoxy-a-D-glucopyranoside

Base Information

• Chemical Name: Methyl4,6-O-benzylidene-3-deoxy-a-D-glucopyranoside
• CAS No.: 65530-28-1
• Molecular Formula: C13H18O5
• Molecular Weight: 266.294
• Hs Code.: 2932999099
• Mol file: 65530-28-1.mol

Synonyms:Methyl4,6-O-benzylidene-3-deoxy-a-D-glucopyranoside;Methyl 3-deoxy-4,6-O-[(R)-phenylmethylene]-alpha-D-ribo-hexopyranoside

Chemical Property of Methyl4,6-O-benzylidene-3-deoxy-a-D-glucopyranoside

Chemical Property:

• Melting Point: 184-184.5 °C
• Boiling Point: 427.1±45.0 °C(Predicted)
• PKA: 13.32±0.60(Predicted)
• PSA: 57.15000
• Density: 1.27±0.1 g/cm3(Predicted)
• LogP: 1.22290

Purity/Quality:

95% ^*data from raw suppliers

Methyl 4,6-O-benzylidene-3-deoxy-a-D-glucopyranoside ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl4,6-O-benzylidene-3-deoxy-a-D-glucopyranoside

There total 19 articles about Methyl4,6-O-benzylidene-3-deoxy-a-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

Methyl 4,6-O-benzylidene-2-O-butyryl-3-deoxy-α-D-ribo-hexopyranoside (157130-84-2) → methyl 4,6-O-benzylidene-3-deoxy-α-D-glucopyranoside (65530-28-1)

Guidance literature:

With sodium methylate; In methanol; for 1h; Ambient temperature;

Reference yield: 84.0%

methyl 2,3-anhydro-4,6-O-benzylidene-2-nitro-α-D-mannopyranoside (85716-67-2) → methyl 4,6-O-benzylidene-3-deoxy-α-D-glucopyranoside (65530-28-1)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 23 ℃; for 0.5h;

DOI:10.1016/j.carres.2007.07.008

Reference yield: 75.0%

4,6-O-benzylidene-1-O-methyl-α-D-glucopyranoside (3162-96-7) → methyl 4,6-O-benzylidene-3-deoxy-α-D-glucopyranoside (65530-28-1)

Guidance literature:

4,6-O-benzylidene-1-O-methyl-α-D-glucopyranoside; With pyridine; p-toluenesulfonyl chloride;

With lithium aluminium tetrahydride; In tetrahydrofuran;

DOI:10.1016/S0040-4039(03)01186-9

upstream raw materials:

benzaldehyde

Methyl 3-deoxy-α-D-ribo-hexopyranoside

Methyl 4,6-O-benzylidene-2-O-butyryl-3-deoxy-α-D-ribo-hexopyranoside

methyl 2,3-anhydro-4,6-benzylidene-α-D-allopyranoside

Downstream raw materials:

methyl 4,6-O-benzylidene-2-O-p-tolylsulfonyl-3-deoxy-α-D-ribo-hexopyranoside

methyl-[O⁴,O⁶-((R)-benzylidene)-O²-methyl-α-D-ribo-3-deoxy-hexopyranoside]

Methyl 2-O-benzyl-4,6-O-benzylidene-3-deoxy-α-D-ribo-hexopyranoside

methyl 4-O-benzyl-3-deoxy-α-D-ribo-hexopyranoside