2-Amino-1-cyclohexylethan-1-ol

Base Information

• Chemical Name: 2-Amino-1-cyclohexylethan-1-ol
• CAS No.: 57230-08-7
• Molecular Formula: C8H17NO
• Molecular Weight: 143.229
• European Community (EC) Number: 863-700-2
• ChEMBL ID: CHEMBL18970
• Nikkaji Number: J401.727G
• Mol file: 57230-08-7.mol

Synonyms:2-amino-1-cyclohexylethan-1-ol;57230-08-7;2-amino-1-cyclohexyl-ethanol;2-AMINO-1-CYCLOHEXYLETHANOL;CHEMBL18970;cyclohexylethanolamine;SCHEMBL133228;MSIAFRBGOYFCND-UHFFFAOYSA-N;BDBM50028785;MFCD13687632;AKOS008118829;AS-18063;FT-0743639;EN300-36150;F2189-0578;Z234895869

Chemical Property of 2-Amino-1-cyclohexylethan-1-ol

Chemical Property:

• PSA: 46.25000
• LogP: 1.58660
• XLogP3: 1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 143.131014166
• Heavy Atom Count: 10
• Complexity: 89.3

Purity/Quality:

99% ^*data from raw suppliers

2-amino-1-cyclohexylethan-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(CC1)C(CN)O

Technology Process of 2-Amino-1-cyclohexylethan-1-ol

There total 10 articles about 2-Amino-1-cyclohexylethan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(+/-)-[1-(tert-butylperoxy)-2-nitroethyl]cyclohexane → 1-amino-2-cyclohexylethan-2-ol (57230-08-7)

Guidance literature:

With palladium on activated charcoal; hydrogen; In methanol; at 20 ℃; Inert atmosphere;

DOI:10.1055/s-0029-1216638

Reference yield: 83.0%

2-cyclohexyl-2-hydroxyacetonitrile (100007-62-3,107485-34-7,4354-47-6) → 1-amino-2-cyclohexylethan-2-ol (57230-08-7)

Guidance literature:

2-cyclohexyl-2-hydroxyacetonitrile; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 25 ℃;

With water; In tetrahydrofuran;

Reference yield: 74.0%

1-cyclohexyl-2-nitroethanol (141377-56-2,141434-99-3,149559-83-1,50598-90-8) → 1-amino-2-cyclohexylethan-2-ol (57230-08-7)

Guidance literature:

With aluminum amalgam; In tetrahydrofuran; water; for 5h;

DOI:10.1016/0040-4039(94)88062-X

upstream raw materials:

2-cyclohexyl-2-hydroxyethanamide

1-oxaspiro<2,5>octane-2-carboxylic acid nitrile

2-cyclohexyl-2-hydroxyacetonitrile

2-Nitro-1-hydroxy-1--aethan

Downstream raw materials:

5-Cyclohexyl-oxazolidin-2-one

(2R)-(-)-1-tert-butoxycarbonylamino-2-cyclohexylethan-2-ol

C₁₅H₂₀N₄O₂S

2-{[3-(1-benzofuran-2-yl)imidazo[1,2-b]pyridazin-6-yl]amino}-1-cyclohexylethanol