Dephospho-CI-920

Base Information

Chemical Name:Dephospho-CI-920
CAS No.:90730-71-5
Molecular Formula:C19H26O6
Molecular Weight:350.4061
Hs Code.:
Nikkaji Number:J2.168.832K
ChEMBL ID:CHEMBL17118
Mol file:90730-71-5.mol

Synonyms:90730-71-5;Dephospho-CI-920;PD 114631;CHEMBL17118;SCHEMBL442794;5,6-Dihydro-6-(3,4,6,13-Tetrahydroxy-3-Methyl-1,7,9,11-Tridecatetrenyl)-2H-Pyran-2-One

Suppliers and Price of Dephospho-CI-920

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of Dephospho-CI-920

Chemical Property:

Vapor Pressure:1.03E-18mmHg at 25°C
Boiling Point:633.6°Cat760mmHg
Flash Point:225.4°C
PSA：107.22000
Density:1.267g/cm³
LogP:0.93810
XLogP3:0.6
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:350.17293854
Heavy Atom Count:25
Complexity:560

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C=CC1CC=CC(=O)O1)(C(CC(C=CC=CC=CCO)O)O)O
Isomeric SMILES:C[C@@](/C=C/[C@H]1CC=CC(=O)O1)([C@@H](C[C@H](/C=C\C=C/C=C/CO)O)O)O

Technology Process of Dephospho-CI-920

There total 15 articles about Dephospho-CI-920 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 87860-39-7,96612-73-6
C₁₉H₂₆O₉P^(1-)*Na⁽¹⁺⁾

: 90730-71-5,96612-64-5
(R)-6-((1E,7Z,9Z,11E)-3,4,6,13-Tetrahydroxy-3-methyl-trideca-1,7,9,11-tetraenyl)-5,6-dihydro-pyran-2-one

Guidance literature:: In water; at 37 ℃; for 7h; alkaline phosphatase;
DOI:10.1021/jo00204a007

Reference yield: 54.0%

: (2E,4Z)-5-iodopenta-2,4-dien-1-ol

: 850146-96-2
(R)-6-[(1E,7Z)-(3R,4R,6R)-8-(Benzyl-dimethyl-silanyl)-6-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-3-methyl-3-triethylsilanyloxy-octa-1,7-dienyl]-5,6-dihydro-pyran-2-one

: 90730-71-5
dephosphofostriecin B

Guidance literature:: With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 - 20 ℃; for 6.5h;
DOI:10.1021/ja042435i

Reference yield:

: 850146-88-2
(R)-1-(Benzyl-dimethyl-silanyl)-6,6-diethoxy-5-hydroxy-hept-1-yn-3-one

: 90730-71-5
dephosphofostriecin B

Guidance literature:: Multi-step reaction with 12 steps

1.1: 88 percent / chiral Ru catalyst / propan-2-ol / 17.5 h / 20 °C

2.1: imidazole / dimethylformamide / 21 h / 20 °C

3.1: 8.52 g / CSA / acetone / 0.67 h / 20 °C

4.1: 97 percent / i-Pr₂NEt; n-Bu₄I / dimethylformamide / 22 h / 40 °C

5.1: allylmagnesium bromide / tetrahydrofuran / 0.33 h / 20 °C

5.2: 75 percent / isopropylmagnesium chloride; s-BuLi / tetrahydrofuran; cyclohexane / 3 h / -78 °C

6.1: 91 percent / aq. HF / acetonitrile; methanol / 4 h / 0 °C

7.1: 99 percent / Pr₂NEt / CH₂Cl₂ / 2 h / 0 °C

8.1: 99 percent / i-Pr₂NEt / CH₂Cl₂ / 0.25 h / 0 °C

9.1: 93 percent / first generation Grubbs catalyst / CH₂Cl₂ / 18 h / Heating

10.1: 94 percent / DDQ; water / CH₂Cl₂ / 4 h / 20 °C

11.1: 53 percent / 2,4,6-tri(iPr)C₆H₂SO₂NHNH₂; NaHCO₃ / methanol / 12 h / 20 °C

12.1: 54 percent / Pd₂(dba)3*CHCl₃; TBAF / tetrahydrofuran / 6.5 h / 0 - 20 °C

With 1H-imidazole; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; Grubbs catalyst first generation; dipropylethylamine; chiral Ru catalyst; trisylhydrazine; camphor-10-sulfonic acid; hydrogen fluoride; tetrabutyl ammonium fluoride; water; sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; allylmagnesium bromide; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; isopropyl alcohol; acetone; acetonitrile;
DOI:10.1021/ja042435i