(S,S)-2,2′-Bipyrrolidine D-tartrate trihydrate

Base Information

• Chemical Name: (S,S)-2,2′-Bipyrrolidine D-tartrate trihydrate
• CAS No.: 136937-03-6
• Molecular Formula: C12H22N2O6
• Molecular Weight: 290.316
• Mol file: 136937-03-6.mol

Synonyms:(S,S)-2,2′-Bipyrrolidine D-tartrate trihydrate;(S,S)-2,2'-Bipyrrolidine D-tartrate trihydrate 99%

Chemical Property of (S,S)-2,2′-Bipyrrolidine D-tartrate trihydrate

Chemical Property:

• Melting Point: 117-118°C (dec.) (lit.)
• PSA: 139.12000
• LogP: -0.97460

Purity/Quality:

98%,99%, ^*data from raw suppliers

(S,S)-2,2′-Bipyrrolidine D-tartrate trihydrate 99% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): 5387052
• Hazard Codes: Xi
• Statements: 36/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S,S)-2,2′-Bipyrrolidine D-tartrate trihydrate

There total 2 articles about (S,S)-2,2′-Bipyrrolidine D-tartrate trihydrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

D-tartaric acid (147-71-7,138508-61-9) + 2,2’-bipyrrolidine (74295-58-2) → (S,S′)-2,2′-bipyrrolidine tartrate (136937-03-6) + C4H6O6*C8H16N2

Guidance literature:

In water; acetic acid; at 0 - 90 ℃;

Reference yield: 55.0%

D-tartaric acid (147-71-7,138508-61-9) + 2,2’-bipyrrolidine (74295-58-2) → (S,S′)-2,2′-bipyrrolidine tartrate (136937-03-6)

Guidance literature:

2,2’-bipyrrolidine; With potassium hydroxide; In water; at 0 ℃; for 0.166667h;

D-tartaric acid; With acetic acid; In water; at 90 ℃;

DOI:10.15227/orgsyn.083.0121

Reference yield: 80.0%

(S,S′)-2,2′-bipyrrolidine tartrate (136937-03-6) → (2S,2′S)-2,2′-bipyrrolidine (124779-66-4)

Guidance literature:

With potassium hydroxide; In water; at 0 ℃; for 0.166667h;

DOI:10.15227/orgsyn.083.0121

upstream raw materials:

D-tartaric acid

2,2’-bipyrrolidine

Downstream raw materials:

(?)?2?(((S)?2?((S)?1?(pyridin?2?ylmethyl)pyrrolidin?2?yl)pyrrolidin?1?yl)methyl)pyridine

(2S,2′S)-[N,N′-bis(1-(2-hydroxy-3,5-di-tert-butylphenylmethyl))]-2,2′-bipyrrolidine

(2S,2'S)-1,1'-bis((5-(2,6-bis(trifluoromethyl)phenyl)pyridin-2-yl)methyl)-2,2'-bipyrrolidine

(2S,2′S)-2,2′-bipyrrolidine