3'-Deoxy-3'-fluoro-xylo-uridine

Base Information

Chemical Name:3'-Deoxy-3'-fluoro-xylo-uridine
CAS No.:129885-95-6
Molecular Formula:C9H11FN2O5
Molecular Weight:246.19
Hs Code.:

Synonyms:3'-Deoxy-3'-fluoro-xylo-uridine

Suppliers and Price of 3'-Deoxy-3'-fluoro-xylo-uridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-((2R,3S,4R,5R)-4-Fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 97%
5mg
$ 880.00

Total 9 raw suppliers

Chemical Property of 3'-Deoxy-3'-fluoro-xylo-uridine

Chemical Property:

Melting Point:158-159 °C
PSA：104.55000
Density:1.63±0.1 g/cm3(Predicted)
LogP:-1.87470

Purity/Quality:

99.3% ^*data from raw suppliers

1-((2R,3S,4R,5R)-4-Fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3'-Deoxy-3'-fluoro-xylo-uridine

There total 10 articles about 3'-Deoxy-3'-fluoro-xylo-uridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: C₁₃H₁₅FN₂O₇

: 129885-95-6
1-(3-deoxy-3-fluoro-β-D-xylofuranosyl)uracil

Guidance literature:: With methanol; ammonia; In acetonitrile; at 20 ℃; for 18h;

Reference yield: 62.0%

: 129885-89-8
1-(3-deoxy-3-fluoro-2,5-di-O-trityl-β-D-xylofuranosyl)uracil

: 129885-95-6
1-(3-deoxy-3-fluoro-β-D-xylofuranosyl)uracil

Guidance literature:: With acetic acid; at 100 ℃; for 6h;
DOI:10.1248/cpb.38.1136

Reference yield:

: 620630-82-2
1,2 5,6-O-di(isopropylidene)-α-D-allofuranose

: 129885-95-6
1-(3-deoxy-3-fluoro-β-D-xylofuranosyl)uracil

Guidance literature:: Multi-step reaction with 8 steps

1: diethylamino-sulfur trifluoride; triethylamine / dichloromethane / -20 °C

2: acetic acid; water / 20 °C

3: sodium periodate / methanol

4: sodium tetrahydroborate / methanol

5: hydrogenchloride / 1,4-dioxane / 20 °C

6: triethylamine; dmap / dichloromethane / 20 °C

7: trimethylsilyl trifluoromethanesulfonate / acetonitrile / 100 °C

8: ammonia; methanol / acetonitrile / 18 h / 20 °C

With hydrogenchloride; methanol; dmap; sodium tetrahydroborate; sodium periodate; diethylamino-sulfur trifluoride; trimethylsilyl trifluoromethanesulfonate; ammonia; water; acetic acid; triethylamine; In 1,4-dioxane; methanol; dichloromethane; acetonitrile;