2-aMino-9-((1R,4S)-4-(hydroxyMethyl)cyclopent-2-enyl)-4,9-dihydro-1H-purin-6(5H)-one

Base Information

Chemical Name:2-aMino-9-((1R,4S)-4-(hydroxyMethyl)cyclopent-2-enyl)-4,9-dihydro-1H-purin-6(5H)-one
CAS No.:112966-73-1
Molecular Formula:C11H15N5O2
Molecular Weight:249.2691
Hs Code.:
Mol file:112966-73-1.mol

Synonyms:2-aMino-9-((1R,4S)-4-(hydroxyMethyl)cyclopent-2-enyl)-4,9-dihydro-1H-purin-6(5H)-one

Suppliers and Price of 2-aMino-9-((1R,4S)-4-(hydroxyMethyl)cyclopent-2-enyl)-4,9-dihydro-1H-purin-6(5H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 5 raw suppliers

Chemical Property of 2-aMino-9-((1R,4S)-4-(hydroxyMethyl)cyclopent-2-enyl)-4,9-dihydro-1H-purin-6(5H)-one

Chemical Property:

PSA：89.85000
LogP:1.32320

Purity/Quality:: 97% ^*data from raw suppliers

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Hazard Codes:

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Technology Process of 2-aMino-9-((1R,4S)-4-(hydroxyMethyl)cyclopent-2-enyl)-4,9-dihydro-1H-purin-6(5H)-one

There total 12 articles about 2-aMino-9-((1R,4S)-4-(hydroxyMethyl)cyclopent-2-enyl)-4,9-dihydro-1H-purin-6(5H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 1071906-28-9
9-[(1S,3R)-3-((tert-butyldiphenylsilyloxy)methyl)cyclopentyl]-9H-purin-6-amine

: 112966-73-1,220285-03-0
[(1R,3S)-3-(6-amino-9H-purin-9-yl)cyclopentyl]methanol

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 2h;
DOI:10.1021/ol801791g

Reference yield:

: 147332-45-4
(1α,4α)-4-(6-Amino-9H-purin-9-yl)-2-cyclopentenylcarbinol

: 112966-73-1,220285-03-0
[(1R,3S)-3-(6-amino-9H-purin-9-yl)cyclopentyl]methanol

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 3h; under 4500.36 Torr;
DOI:10.1002/hlca.200390093

Reference yield:

: 918492-97-4
(1S,cis)-4-[(5-amino-6-chloro-4-pyrimidinyl)amino]-2-cyclopentene-1-methanol

: 112966-73-1,220285-03-0
[(1R,3S)-3-(6-amino-9H-purin-9-yl)cyclopentyl]methanol

Guidance literature:: Multi-step reaction with 3 steps

1: 13.3 g / methanesulfonic acid / 4 h

2: 2.8 g / NH₃ / 18 h / 25 °C

3: 350 mg / H₂ / Pd/C / ethanol / 12 h / 2068.59 Torr

With methanesulfonic acid; ammonia; hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm060776w